Recent Submissions

  • Mutations underlying Episodic Ataxia type-1 antagonize Kv1.1 RNA editing 

    Ferrick-Kiddie, Elizabeth A.; Rosenthal, Joshua J. C.; Ayers, Gregory D.; Emeson, Ronald B. (Nature Publishing Group, 2017-02-20)
    Adenosine-to-inosine RNA editing in transcripts encoding the voltage-gated potassium channel Kv1.1 converts an isoleucine to valine codon for amino acid 400, speeding channel recovery from inactivation. Numerous Kv1.1 ...
  • HIV glycoprotein Gp120 impairs fast axonal transport by activating Tak1 signaling pathways 

    Berth, Sarah; Mesnard-Hoaglin, Nichole; Wang, Bin; Kim, Hajwa; Song, Yuyu; Sapar, Maria; Morfini, Gerardo A.; Brady, Scott T. (Sage, 2016-11-01)
    Sensory neuropathies are the most common neurological complication of HIV. Of these, distal sensory polyneuropathy (DSP) is directly caused by HIV infection and characterized by length-dependent axonal degeneration of ...
  • Introducing the microbiome into Precision Medicine 

    Kuntz, Thomas M.; Gilbert, Jack A. (2016-11)
    Understanding how individual people respond to medical therapy is a key facet of improving the odds ratio that interventions will have a positive impact. Reducing the non-responder rate for an intervention or reducing ...
  • Comparative mitochondrial and chloroplast genomics of a genetically distinct form of Sargassum contributing to recent “Golden Tides” in the Western Atlantic 

    Amaral-Zettler, Linda A.; Dragone, Nicholas B.; Schell, Jeffrey M.; Slikas, Beth; Murphy, Leslie G.; Morrall, Clare E.; Zettler, Erik R. (John Wiley & Sons, 2016-12-20)
    Over the past 5 years, massive accumulations of holopelagic species of the brown macroalga Sargassum in coastal areas of the Caribbean have created “golden tides” that threaten local biodiversity and trigger economic losses ...
  • Disturbance regimes predictably alter diversity in an ecologically complex bacterial system 

    Gibbons, Sean M.; Scholz, Monika; Hutchison, Alan L.; Dinner, Aaron R.; Gilbert, Jack A.; Coleman, Maureen L. (American Society for Microbiology, 2016-12-20)
    Diversity is often associated with the functional stability of ecological communities from microbes to macroorganisms. Understanding how diversity responds to environmental perturbations and the consequences of this ...
  • Physical basis of large microtubule aster growth 

    Ishihara, Keisuke; Korolev, Kirill S.; Mitchison, Timothy J. (eLife, 2016-11-28)
    Microtubule asters - radial arrays of microtubules organized by centrosomes - play a fundamental role in the spatial coordination of animal cells. The standard model of aster growth assumes a fixed number of microtubules ...
  • Patient-specific Bacteroides genome variants in pouchitis 

    Vineis, Joseph H.; Ringus, Daina L.; Morrison, Hilary G.; Delmont, Tom O.; Dalal, Sushila R.; Raffals, Laura E.; Antonopoulos, Dionysios A.; Rubin, David T.; Eren, A. Murat; Chang, Eugene B.; Sogin, Mitchell L. (American Society for Microbiology, 2016-11-15)
    A 2-year longitudinal microbiome study of 22 patients who underwent colectomy with an ileal pouch anal anastomosis detected significant increases in distinct populations of Bacteroides during 9 of 11 patient visits that ...
  • How do we make indoor environments and healthcare settings healthier? 

    Gilbert, Jack A. (John Wiley & Sons, 2016-10-17)
    It is now well accepted that our modern lifestyle has certain implications for our health (Schaub et al., 2006), mainly as a result of our willingness to remove ourselves from the biological diversity of our natural ...
  • Carbon dioxide fluxes reflect plant zonation and belowground biomass in a coastal marsh 

    Moseman-Valtierra, Serena M.; Abdul-Aziz, Omar I.; Tang, Jianwu; Ishtiaq, Khandker S.; Morkeski, Kate; Mora, Jordan; Quinn, Ryan K.; Martin, Rose M.; Egan, Katherine E.; Brannon, Elizabeth Q.; Carey, Joanna C.; Kroeger, Kevin D. (John Wiley & Sons, 2016-11-15)
    Coastal wetlands are major global carbon sinks; however, they are heterogeneous and dynamic ecosystems. To characterize spatial and temporal variability in a New England salt marsh, greenhouse gas (GHG) fluxes were compared ...
  • Cell culture protocols, HeLa and CHO cells Woods Hole Physiology Course, 2006 

    Altman, David (Marine Biological Laboratory, 2006)
  • Shortening of microtubule overlap regions defines membrane delivery sites during plant cytokinesis 

    de Keijzer, Jeroen; Kieft, Henk; Ketelaar, Tijs; Goshima, Gohta; Janson, Marcel E. (2016-12)
    Different from animal cells that divide by constriction of the cortex inwards, cells of land plants divide by initiating a new cell wall segment from their centre. For this, a disk-shaped, membrane-enclosed precursor ...
  • Ecosystem responses to climate change at a Low Arctic and a High Arctic long-term research site 

    Hobbie, John E.; Shaver, Gaius R.; Rastetter, Edward B.; Cherry, Jessica E.; Goetz, Scott J.; Guay, Kevin C.; Gould, William A.; Kling, George W. (Springer, 2017-01-23)
    Long-term measurements of ecological effects of warming are often not statistically significant because of annual variability or signal noise. These are reduced in indicators that filter or reduce the noise around the ...
  • Evidence for microbial mediation of subseafloor nitrogen redox processes at Loihi Seamount, Hawaii 

    Sylvan, Jason B.; Wankel, Scott D.; LaRowe, Douglas E.; Charoenpong, Chawalit N.; Huber, Julie A.; Moyer, Craig L.; Edwards, Katrina J. (2016-10-24)
    The role of nitrogen cycling in submarine hydrothermal systems is far less studied than that of other biologically reactive elements such as sulfur and iron. In order to address this knowledge gap, we investigated nitrogen ...
  • Is axonal degeneration a key early event in Parkinson’s disease? 

    Kurowska, Zuzanna; Kordower, Jeffrey H.; Stoessl, A Jon; Burke, Robert E.; Brundin, Patrik; Yue, Zhenyu; Brady, Scott T.; Milbrandt, Jeffrey; Trapp, Bruce D.; Sherer, Todd B.; Medicetty, Satish (2016-06)
    Recent research suggests that in Parkinson’s disease the long, thin and unmyelinated axons of dopaminergic neurons degenerate early in the disease process. We organized a workshop entitled ‘Axonal Pathology in Parkinson’s ...
  • Dynamic masquerade with morphing 3D skin in cuttlefish 

    Panetta, Deanna; Buresch, Kendra C.; Hanlon, Roger (2017-02-03)
    Masquerade is a defence tactic in which a prey resembles an inedible or inanimate object thus causing predators to misclassify it. Most masquerade colour patterns are static although some species adopt postures or behaviours ...
  • Tracking recurrence of correlation structure in neuronal recordings 

    Neymotin, Samuel A.; Talbot, Zoe N.; Jung, Jeeyune Q.; Fenton, André A.; Lytton, William W. (Elsevier, 2016-10-13)
    Correlated neuronal activity in the brain is hypothesized to contribute to information representation, and is important for gauging brain dynamics in health and disease. Due to high dimensional neural datasets, it is ...
  • Extreme rainfall and snowfall alter responses of soil respiration to nitrogen fertilization : a 3-year field experiment 

    Chen, Zengming; Xu, Yehong; Zhou, Xuhui; Tang, Jianwu; Kuzyakov, Yakov; Yu, Hongyan; Fan, Jianling; Ding, Weixin (2016-12)
    Extreme precipitation is predicted to be more frequent and intense accompanying global warming, and may have profound impacts on soil respiration (Rs) and its components, i.e., autotrophic (Ra) and heterotrophic (Rh) ...
  • Mapping optical path length and image enhancement using quantitative orientation-independent differential interference contrast microscopy 

    Shribak, Michael; Larkin, Kieran G.; Biggs, David (SPIE, 2017-01-06)
    We describe the principles of using orientation-independent differential interference contrast (OI-DIC) microscopy for mapping optical path length (OPL). Computation of the scalar two-dimensional OPL map is based on an ...
  • Solute and sediment export from Amazon forest and soybean headwater streams 

    Riskin, Shelby H.; Neill, Christopher; Jankowski, KathiJo; Krusche, Alex V.; McHorney, Richard; Elsenbeer, Helmut; Macedo, Marcia N.; Nunes, Darlisson; Porder, Stephen (John Wiley & Sons, 2017-01-04)
    Intensive cropland agriculture commonly increases streamwater solute concentrations and export from small watersheds. In recent decades, the lowland tropics have become the world's largest and most important region of ...
  • Lateralization of eye use in cuttlefish : opposite direction for anti-predatory and predatory behaviors 

    Schnell, Alexandra K.; Hanlon, Roger T.; Benkada, Aïcha; jozet-alves, christelle (Frontiers Media, 2016-12-12)
    Vertebrates with laterally placed eyes typically exhibit preferential eye use for ecological activities such as scanning for predators or prey. Processing visual information predominately through the left or right visual ...

View more