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The Marine Biological Laboratory is an international center for research, education, and training in biology, biomedicine, and ecology.
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Leuckart Wall Charts
Scans of the Leuckart Wall Charts held at the MBLWHOI Library in Woods Hole, Massachusetts.
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Modulation of G(q)/PLC-mediated signaling by acute lithium exposure
(Frontiers Media, 2022-02-15)Although lithium has long been one of the most widely used pharmacological agents in psychiatry, its mechanisms of action at the cellular and molecular levels remain poorly understood. One of the targets of Li+ is the ... -
The transcriptional response of soil bacteria to long-term warming and short-term seasonal fluctuations in a terrestrial forest
(Frontiers Media, 2021-08-27)Terrestrial ecosystems are an important carbon store, and this carbon is vulnerable to microbial degradation with climate warming. After 30 years of experimental warming, carbon stocks in a temperate mixed deciduous forest ... -
Physical properties of the cytoplasm modulate the rates of microtubule polymerization and depolymerization
(Elsevier, 2022-02-28)The cytoplasm is a crowded, visco-elastic environment whose physical properties change according to physiological or developmental states. How the physical properties of the cytoplasm impact cellular functions in vivo ... -
Differential adhesion regulates neurite placement via a retrograde zippering mechanism
(eLife Sciences Publications, 2021-11-16)During development, neurites and synapses segregate into specific neighborhoods or layers within nerve bundles. The developmental programs guiding placement of neurites in specific layers, and hence their incorporation ... -
Regulation of stem cell identity by miR-200a during spinal cord regeneration
(Company of Biologists, 2022-02-14)Axolotls are an important model organism for multiple types of regeneration, including functional spinal cord regeneration. Remarkably, axolotls can repair their spinal cord after a small lesion injury and can also regenerate ... -
Pupil dilation and constriction in the skate Leucoraja erinacea in a simulated natural light field
(The Company of Biologists, 2022-02-14)The skate Leucoraja erinacea has an elaborately shaped pupil, whose characteristics and functions have received little attention. The goal of our study was to investigate the pupil response in relation to natural ambient ... -
Tracking calcium dynamics from individual neurons in behaving animals
(Public Library of Science, 2021-10-08)Measuring the activity of neuronal populations with calcium imaging can capture emergent functional properties of neuronal circuits with single cell resolution. However, the motion of freely behaving animals, together with ... -
Variation in sediment and seagrass characteristics reflect multiple stressors along a nitrogen-enrichment gradient in a New England lagoon
(Association for the Sciences of Limnology and Oceanography, 2022-01-28)We examined concentrations of organic carbon, dissolved sulfides, total sediment sulfur, and stable sulfur isotope ratios in seagrass leaf tissues across a nitrogen-enrichment gradient in a coastal marine ecosystem (Cape ... -
Editorial: microbial communities and metabolisms involved in the degradation of cellular and extracellular organic biopolymers
(Frontiers Media, 2022-01-04)Most organic matter on Earth occurs in the form of macromolecules and complex biopolymers, which include the building blocks of every organism. Plant, animal, fungal, and microbial cells largely consist of macromolecules ... -
Ramisyllis kingghidorahi n. Sp., a new branching annelid from Japan
(Springer, 2022-01-19)Among over 20,000 species of Annelida, only two branching species with a highly modified body-pattern are known until now: the Syllidae Syllis ramosa McIntosh, 1879, and Ramisyllis multicaudata Glasby et al. (Zoological ... -
Common environmental pollutants negatively affect development and regeneration in the sea anemone Nematostella vectensis holobiont
(Frontiers Media, 2021-12-23)The anthozoan sea anemone Nematostella vectensis belongs to the phylum of cnidarians which also includes jellyfish and corals. Nematostella are native to United States East Coast marsh lands, where they constantly adapt ... -
Modeling nitrous oxide emissions from large-scale intensive cropping systems in the southern Amazon
(Frontiers Media, 2021-12-10)Nitrogen (N) fertilizer use is rapidly intensifying on tropical croplands and has the potential to increase emissions of the greenhouse gas, nitrous oxide (N2O). Since about 2005 Mato Grosso (MT), Brazil has shifted from ... -
Biogeography of ammonia oxidizers in New England and Gulf of Mexico salt marshes and the potential importance of comammox
(Springer, 2021-03-29)Few studies have focused on broad scale biogeographic patterns of ammonia oxidizers in coastal systems, yet understanding the processes that govern them is paramount to understanding the mechanisms that drive biodiversity, ... -
TIAMMAt: leveraging biodiversity to revise protein domain models, evidence from innate immunity
(Oxford University Press, 2021-08-30)Sequence annotation is fundamental for studying the evolution of protein families, particularly when working with nonmodel species. Given the rapid, ever-increasing number of species receiving high-quality genome sequencing, ... -
Uncovering the effects of symbiosis and temperature on coral calcification
(University of Chicago Press, 2022-01-10)We tested the impact of temperature and symbiont state on calcification in corals, using the facultatively symbiotic coral Astrangia poculata as a model system. Symbiotic and aposymbiotic colonies of A. poculata were reared ... -
The lesser Pacific Striped Octopus, Octopus chierchiae: an emerging laboratory model
(Frontiers Media, 2021-12-13)Cephalopods have the potential to become useful experimental models in various fields of science, particularly in neuroscience, physiology, and behavior. Their complex nervous systems, intricate color- and texture-changing ... -
Adaptive proteome diversification by nonsynonymous A-to-I RNA editing in coleoid cephalopods
(Oxford University Press, 2021-05-22)RNA editing by the ADAR enzymes converts selected adenosines into inosines, biological mimics for guanosines. By doing so, it alters protein-coding sequences, resulting in novel protein products that diversify the proteome ... -
Machine-learning-based evaluation of intratumoral heterogeneity and tumor-stroma interface for clinical guidance
(Elsevier, 2021-09-21)Assessment of intratumoral heterogeneity and tumor-host interaction within the tumor microenvironment is becoming increasingly important for innovative cancer therapy decisions because of the unique information it can ... -
Environmentally friendly and efficient hornet nest envelope-based photothermal absorbers
(American Chemical Society, 2021-12-07)Water shortage is a critical global issue that threatens human health, environmental sustainability, and the preservation of Earth’s climate. Desalination from seawater and sewage is a promising avenue for alleviating this ... -
Synuclein regulates synaptic vesicle clustering and docking at a vertebrate synapse
(Frontiers Media, 2021-11-26)Neurotransmission relies critically on the exocytotic release of neurotransmitters from small synaptic vesicles (SVs) at the active zone. Therefore, it is essential for neurons to maintain an adequate pool of SVs clustered ...
