Recent Submissions

  • Absolute proteomic quantification reveals design principles of sperm flagellar chemosensation 

    Trotschel, Christian; Hamzeh, Hussein; Alvarez, Luis; Pascal, René; Lavryk, Fedir; Bönigk, Wolfgang; Körschen, Heinz Gerd; Müller, Astrid; Poetsch, Ansgar; Rennhack, Andreas; Gui, Long; Nicastro, Daniela; Strünker, Timo; Seifert, Reinhard; Kaupp, U. Benjamin (EMBO Press, 2019-12-27)
    Cilia serve as cellular antennae that translate sensory information into physiological responses. In the sperm flagellum, a single chemoattractant molecule can trigger a Ca2+ rise that controls motility. The mechanisms ...
  • A de novo reference transcriptome for Bolitoglossa vallecula, an Andean mountain salamander in Colombia 

    Arenas Gómez, Claudia Marcela; Woodcock, M. Ryan; Smith, Jeramiah J.; Voss, S. Randal; Delgado, Jean Paul (Elsevier, 2020-02-11)
    The amphibian order Caudata, contains several important model species for biological research. However, there is need to generate transcriptome data from representative species of the primary salamander families. Here we ...
  • 12-h clock regulation of genetic information flow by XBP1s 

    Pan, Yinghong; Ballance, Heather; Meng, Huan; Gonzalez, Naomi; Kim, Sam-Moon; Abdurehman, Leymaan; York, Brian; Chen, Xi; Schnytzer, Yisrael; Levy, Oren; Dacso, Clifford C.; McClung, Colleen A.; O’Malley, Bert W.; Liu, Silvia; Zhu, Bokai (Public Library of Science, 2020-01-14)
    Our group recently characterized a cell-autonomous mammalian 12-h clock independent from the circadian clock, but its function and mechanism of regulation remain poorly understood. Here, we show that in mouse liver, ...
  • Methane oxidation and methylotroph population dynamics in groundwater mesocosms 

    Kuloyo, Olukayode; Ruff, S. Emil; Cahill, Aaron; Connors, Liam; Zorz, Jackie K.; Hrabe de Angelis, Isabella; Nightingale, Michael; Mayer, Bernhard; Strous, Marc (Wiley, 2020-02-03)
    Extraction of natural gas from unconventional hydrocarbon reservoirs by hydraulic fracturing raises concerns about methane migration into groundwater. Microbial methane oxidation can be a significant methane sink. Here, ...
  • The various routes to functional regeneration in the central nervous system 

    Echeverri, Karen (Nature Research, 2020-01-29)
    The axolotl is a type of Mexican salamander with astonishing regenerative capacity1. In our recent paper, we identified a signaling heterodimer that is formed directly after injury in the glial cells adjacent to the injury ...
  • Phosphorylation of nephrin induces phase separated domains that move through actomyosin contraction 

    Kim, Soyeon; Kalappurakkal, Joseph Mathew; Mayor, Satyajit; Rosen, Michael K. (American Society for Cell Biology, 2019-11-14)
    The plasma membrane of eukaryotic cells is organized into lipid and protein microdomains, whose assembly mechanisms and functions are incompletely understood. We demonstrate that proteins in the nephrin/Nck/N-WASP ...
  • A cerebellum-like circuit in the lateral line system of fish cancels mechanosensory input associated with its own movements 

    Perks, Krista E.; Krotinger, Anna; Bodznick, David (Company of Biologists, 2020-01-17)
    An animal's own movement exerts a profound impact on sensory input to its nervous system. Peripheral sensory receptors do not distinguish externally generated stimuli from stimuli generated by an animal's own behavior ...
  • Microbial community dynamics and coexistence in a sulfide-driven phototrophic bloom 

    Bhatnagar, Srijak; Cowley, Elise S.; Kopf, Sebastian H.; Pérez Castro, Sherlynette; Kearney, Sean; Dawson, Scott C.; Hanselmann, Kurt; Ruff, S. Emil (Wiley, 2020-01-17)
    Background: Lagoons are common along coastlines worldwide and are important for biogeochemical element cycling, coastal biodiversity, coastal erosion protection and blue carbon sequestration. These ecosystems are frequently ...
  • A draft genome sequence of the elusive giant squid, Architeuthis dux 

    da Fonseca, Rute R.; Couto, Alvarina; Machado, Andre M.; Brejova, Brona; Albertin, Carolin B.; Silva, Filipe; Gardner, Paul; Baril, Tobias; Hayward, Alex; Campos, Alexandre; Ribeiro, Ângela M.; Barrio-Hernandez, Inigo; Hoving, Henk-Jan; Tafur-Jimenez, Ricardo; Chu, Chong; Frazão, Barbara; Petersen, Bent; Peñaloza, Fernando; Musacchia, Francesco; Alexander, Graham C., Jr.; Osório, Hugo; Winkelmann, Inger; Simakov, Oleg; Rasmussen, Simon; Rahman, M. Ziaur; Pisani, Davide; Vinther, Jakob; Jarvis, Erich; Zhang, Guojie; Strugnell, Jan M.; Castro, L. Filipe C.; Fedrigo, Olivier; Patricio, Mateus; Li, Qiye; Rocha, Sara; Antunes, Agostinho; Wu, Yufeng; Ma, Bin; Sanges, Remo; Vinar, Tomas; Blagoev, Blagoy; Sicheritz-Ponten, Thomas; Nielsen, Rasmus; Gilbert, M. Thomas P. (Oxford University Press, 2020-01-16)
    Background: The giant squid (Architeuthis dux; Steenstrup, 1857) is an enigmatic giant mollusc with a circumglobal distribution in the deep ocean, except in the high Arctic and Antarctic waters. The elusiveness of the ...
  • Hsc70 ameliorates the vesicle recycling defects caused by excess alpha-synuclein at synapses 

    Banks, Susan M. L.; Medeiros, Audrey T.; McQuillan, Molly; Busch, David J.; Ibarraran-Viniegra, Ana Sofia; Sousa, Rui; Lafer, Eileen M.; Morgan, Jennifer R. (Society for Neuroscience, 2020-01-15)
    α-Synuclein overexpression and aggregation are linked to Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and several other neurodegenerative disorders. In addition to effects in the cell body, α-synuclein ...
  • Invasive tunicate (Ascidiacea) metabolic and filtration rates in comparison to native tunicate and bivalve species 

    Zhang, Yingqi; Deegan, Linda A.; Carman, Mary R. (Regional Euro-Asian Biological Invasions Centre, 2019-10-30)
    Several invasive species of tunicates (Ascidiacea) have become cosmopolitan and widely distributed in coastal areas worldwide over the past few decades. These nonindigenous tunicates have consequently caused fouling problems ...
  • Specialization for rapid excitation in fast squid tentacle muscle involves action potentials absent in slow arm muscle 

    Gilly, William; Renken, Corbin; Rosenthal, Joshua J. C.; Kier, William M. (Company of Biologists, 2020-01-03)
    An important aspect of the performance of many fast muscle fiber types is rapid excitation. Previous research on the cross-striated muscle fibers responsible for the rapid tentacle strike in squid has revealed the ...
  • Reorganization of complex ciliary flows around regenerating Stentor coeruleus 

    Wan, Kirsty Y.; Hürlimann, Sylvia K.; Fenix, Aidan M.; McGillivary, Rebecca M.; Makushok, Tatyana; Burns, Evan; Sheung, Janet Y.; Marshall, Wallace F. (The Royal Society, 2019-12-30)
    The phenomenon of ciliary coordination has garnered increasing attention in recent decades and multiple theories have been proposed to explain its occurrence in different biological systems. While hydrodynamic interactions ...
  • A scalable culturing system for the marine annelid Platynereis dumerilii 

    Kuehn, Emily; Stockinger, Alexander W.; Girard, Jerome; Raible, Florian; Ozpolat, B. Duygu (Public Library of Science, 2019-12-05)
    Platynereis dumerilii is a marine segmented worm (annelid) with externally fertilized embryos and it can be cultured for the full life cycle in the laboratory. The accessibility of embryos and larvae combined with the ...
  • Molecular profiling of single neurons of known identity in two ganglia from the crab Cancer borealis 

    Northcutt, Adam J.; Kick, Daniel R.; Otopalik, Adriane G; Goetz, Benjamin M.; Harris, Rayna M.; Santin, Joseph M.; Hofmann, Hans A.; Marder, Eve; Schulz, David J. (National Academy of Sciences, 2019-12-05)
    Understanding circuit organization depends on identification of cell types. Recent advances in transcriptional profiling methods have enabled classification of cell types by their gene expression. While exceptionally ...
  • Tidal wetland resilience to sea level rise increases their carbon sequestration capacity in United States 

    Wang, Faming; Lu, Xiaoliang; Sanders, Christian J.; Tang, Jianwu (Nature Research, 2019-11-28)
    Coastal wetlands are large reservoirs of soil carbon (C). However, the annual C accumulation rates contributing to the C storage in these systems have yet to be spatially estimated on a large scale. We synthesized C ...
  • Seasons of Syn 

    Hunter-Cevera, Kristen R.; Neubert, Michael G.; Olson, Robert J.; Shalapyonok, Alexi; Solow, Andrew R.; Sosik, Heidi M. (Wiley, 2019-11-19)
    Synechococcus is a widespread and important marine primary producer. Time series provide critical information for identifying and understanding the factors that determine abundance patterns. Here, we present the results ...
  • Plant uptake offsets silica release from a large arctic tundra wildfire 

    Carey, Joanna C.; Abbott, Benjamin W.; Rocha, Adrian V. (American Geophysical Union, 2019-07-24)
    Rapid climate change at high latitudes is projected to increase wildfire extent in tundra ecosystems by up to fivefold by the end of the century. Tundra wildfire could alter terrestrial silica (SiO2) cycling by restructuring ...
  • Male alternative reproductive tactics and associated evolution of anatomical characteristics in loliginid squid 

    Marian, José E. A. R.; Apostólico, Lígia H.; Chiao, Chuan-Chin; Hanlon, Roger T.; Hirohashi, Noritaka; Iwata, Yoko; Mather, Jennifer; Sato, Noriyosi; Shaw, Paul W. (Frontiers Media, 2019-10-15)
    Loliginid squids provide a unique model system to explore male alternative reproductive tactics (ARTs) and their linkage to size, behavioral decision making, and possibly age. Large individuals fight one another and the ...
  • Thrust generation during steady swimming and acceleration from rest in anguilliform swimmers 

    Du Clos, Kevin; Dabiri, John O.; Costello, John H.; Colin, Sean P.; Morgan, Jennifer R.; Fogerson, Stephanie M.; Gemmell, Brad J. (Company of Biologists, 2019-11-18)
    Escape swimming is a crucial behavior by which undulatory swimmers evade potential threats. The hydrodynamics of escape swimming have not been well studied, particularly for anguilliform swimmers, such as the sea lamprey ...

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