Recent Submissions

  • The synaptic vesicle cycle revisited: New insights into the modes and mechanisms 

    Chanaday, Natali L.; Cousin, Michael A.; Milosevic, Ira; Watanabe, Shigeki; Morgan, Jennifer R. (Society for Neuroscience, 2019-10-16)
    Neurotransmission is sustained by endocytosis and refilling of synaptic vesicles (SVs) locally within the presynapse. Until recently, a consensus formed that after exocytosis, SVs are recovered by either fusion pore closure ...
  • Interaction between pollution and climate change augments ecological risk to a coastal ecosystem 

    Lu, Yonglong; Wang, Ruoshi; Shi, Yajuan; Su, Chao; Yuan, Jingjing; Johnson, Andrew C.; Jenkins, Alan; Ferrier, Robert C.; Chen, Deliang; Tian, Hanqin; Melillo, Jerry M.; Song, Shuai; Ellison, Aaron M. (Taylor & Francis, 2018-07-31)
    Pollution and climate change are among the most challenging issues for countries with developing economies, but we know little about the ecological risks that result when these pressures occur together. We explored direct ...
  • Venomic, transcriptomic, and bioactivity analyses of Pamphobeteus verdolaga venom reveal complex disulfide-rich peptides that modulate calcium channels 

    Estrada-Gomez, Sebastian; Caldas Cardoso, Fernanda; Vargas-Muñoz, Leidy Johana; Quintana-Castillo, Juan Carlos; Arenas Gómez, Claudia Marcela; Pineda, Sandy Steffany; Saldarriaga-Cordoba, Monica Maria (MDPI, 2019-08-27)
    Pamphobeteus verdolaga is a recently described Theraphosidae spider from the Andean region of Colombia. Previous reports partially characterized its venom profile. In this study, we conducted a detailed analysis that ...
  • A quantitative screen for metabolic enzyme structures reveals patterns of assembly across the yeast metabolic network 

    Noree, Chalongrat; Begovich, Kyle; Samilo, Dane; Broyer, Risa; Monfort, Elena; Wilhelm, James E. (American Society for Cell Biology, 2019-09-30)
    Despite the proliferation of proteins that can form filaments or phase-separated condensates, it remains unclear how this behavior is distributed over biological networks. We have found that 60 of the 440 yeast metabolic ...
  • Hurricanes enhance labile carbon export to the deep ocean 

    Pedrosa-Pamies, Rut; Conte, Maureen H.; Weber, John C.; Johnson, Rodney (American Geophysical Union, 2019-08-16)
    Tropical cyclones (hurricanes) generate intense surface ocean cooling and vertical mixing resulting in nutrient upwelling into the photic zone and episodic phytoplankton blooms. However, their influence on the deep ocean ...
  • Soil warming accelerates biogeochemical silica cycling in a temperate forest. 

    Gewirtzman, Jonathan; Tang, Jianwu; Melillo, Jerry M.; Werner, William J.; Kurtz, Andrew C.; Fulweiler, Robinson W.; Carey, Joanna C. (Frontiers Media, 2019-09-11)
    Biological cycling of silica plays an important role in terrestrial primary production. Soil warming stemming from climate change can alter the cycling of elements, such as carbon and nitrogen, in forested ecosystems. ...
  • Hypoxia has a lasting effect on fast-startle behavior of the tropical fish Haemulon plumieri 

    Sánchez-García, Mayra A.; Zottoli, Steven J.; Roberson, Loretta M. (University of Chicago Press, 2019-07-16)
    Anthropogenic activities and climate change have resulted in an increase of hypoxic conditions in nearshore ecosystems worldwide. Depending on the persistence of a hypoxic event, the survival of aquatic animals can be ...
  • Computational history of knowledge: Challenges and opportunities 

    Laubichler, Manfred D.; Maienschein, Jane; Renn, Jurgen (University of Chicago Press, 2019-09)
    So far, the twenty-first century has been defined by an ever-increasing availability of digital data and substantial advances in computational methods. Taken together, these developments have already affected all aspects ...
  • Introduction 

    Gibson, Abraham; Laubichler, Manfred D.; Maienschein, Jane (University of Chicago Press, 2019-09)
    Digital technologies have transformed both the historical record and the historical profession. This Focus section examines how computational methods have influenced, and will influence, the history of science. The essays ...
  • The life cycle of the Acropora coral-eating flatworm (AEFW), Prosthiostomum acroporae; the influence of temperature and management guidelines 

    Barton, Jonathan A.; Hutson, Kate S.; Bourne, David G.; Humphrey, Craig; Dybala, Cat; Rawlinson, Kate A. (Frontiers Media, 2019-09-04)
    As coral aquaculture is increasing around the world for reef restoration and trade, mitigating the impact of coral predators, pathogens and parasites is necessary for optimal growth. The Acropora coral-eating flatworm ...
  • Maneuvering performance in the colonial siphonophore, Nanomia bijuga 

    Sutherland, Kelly R.; Gemmell, Brad J.; Colin, Sean P.; Costello, John H. (MDPI, 2019-09-05)
    The colonial cnidarian, Nanomia bijuga, is highly proficient at moving in three-dimensional space through forward swimming, reverse swimming and turning. We used high speed videography, particle tracking, and particle image ...
  • Tetrodotoxin-sensitive sodium channels mediate action potential firing and excitability in menthol-sensitive Vglut3-lineage sensory neurons 

    Griffith, Theanne N.; Docter, Trevor A.; Lumpkin, Ellen A. (Society for Neuroscience, 2019-09-04)
    Small-diameter vesicular glutamate transporter 3-lineage (Vglut3lineage) dorsal root ganglion (DRG) neurons play an important role in mechanosensation and thermal hypersensitivity; however, little is known about their ...
  • Supporting Spartina: Interdisciplinary perspective shows spartina as a distinct solid genus 

    Bortolus, Alejandro; Adam, Paul; Adams, Janine B.; Ainouche, Malika L.; Ayres, Debra; Bertness, Mark D.; Bouma, Tjeerd J.; Bruno, John F.; Caçador, Isabel; Carlton, James T.; Castillo, Jesus M.; Costa, Cesar S.B.; Davy, Anthony J.; Deegan, Linda A.; Duarte, Bernardo; Figueroa, Enrique; Gerwein, Joel; Gray, Alan J.; Grosholz, Edwin D.; Hacker, Sally D.; Hughes, A. Randall; Mateos‐Naranjo, Enrique; Mendelssohn, Irving A.; Morris, James T.; Muñoz‐Rodríguez, Adolfo F.; Nieva, Francisco J.J.; Levin, Lisa A.; Li, Bo; Liu, Wenwen; Pennings, Steven C.; Pickart, Andrea; Redondo‐Gómez, Susana; Richardson, David M.; Salmon, Armel; Schwindt, Evangelina; Silliman, Brian; Sotka, Erik E.; Stace, Clive; Sytsma, Mark; Temmerman, Stijn; Turner, R. Eugene; Valiela, Ivan; Weinstein, Michael P.; Weis, Judith S. (Ecological Society of America, 2019-09-19)
    In 2014, a DNA‐based phylogenetic study confirming the paraphyly of the grass subtribe Sporobolinae proposed the creation of a large monophyletic genus Sporobolus, including (among others) species previously included in ...
  • Nitrogen cycle patterns during forest regrowth in an African Miombo woodland landscape 

    Mayes, Marc; Melillo, Jerry M.; Neill, Christopher; Palm, Cheryl; Mustard, Jack; Nyadzi, Gerson (American Geophysical Union, 2019-05-08)
    Tropical dry forests in eastern and southern Africa cover 2.5 × 106 km2, support wildlife habitat and livelihoods of more than 150 million people, and face threats from land use and climate change. To inform conservation, ...
  • The ventral epithelium of Trichoplax adhaerens deploys in distinct patterns cells that secrete digestive enzymes, mucus or diverse neuropeptides 

    Mayorova, Tatiana D.; Hammar, Katherine M.; Winters, Christine A.; Reese, Thomas S.; Smith, Carolyn L. (Company of Biologists, 2019-08-09)
    The disk-shaped millimeter-sized marine animal, Trichoplax adhaerens, is notable because of its small number of cell types and primitive mode of feeding. It glides on substrates propelled by beating cilia on its lower ...
  • The Chlamydomonas flagellar membrane glycoprotein FMG-1B is necessary for expression of force at the flagellar surface 

    Bloodgood, Robert A.; Tetreault, Joseph; Sloboda, Roger D. (Company of Biologists, 2019-08-19)
    In addition to bend propagation for swimming, Chlamydomonas cells use their flagella to glide along a surface. When polystyrene microspheres are added to cells, they attach to and move along the flagellar surface, thus ...
  • Pectin chemistry and cellulose crystallinity govern pavement cell morphogenesis in a multi-step mechanism 

    Altartouri, Bara; Bidhendi, Amir J.; Tani, Tomomi; Suzuki, Johnny; Conrad, Christina; Chebli, Youssef; Liu, Na; Karunakaran, Chithra; Scarcelli, Giuliano; Geitmann, Anja (American Society of Plant Biologists, 2019-08-29)
    Simple plant cell morphologies, such as cylindrical shoot cells, are determined by the extensibility pattern of the primary cell wall, which is thought to be largely dominated by cellulose microfibrils, but the mechanism ...
  • Future nitrogen availability and its effect on carbon sequestration in Northern Eurasia 

    Kicklighter, David W.; Melillo, Jerry M.; Monier, Erwan; Sokolov, Andrei P.; Zhuang, Qianlai (Nature Research, 2019-07-09)
    Nitrogen (N) availability exerts strong control on carbon storage in the forests of Northern Eurasia. Here, using a process-based model, we explore how three factors that alter N availability—permafrost degradation, ...
  • Construction and composition of the squid pen from Doryteuthis pealeii 

    Messerli, Mark A.; Raihan, M. Jahir; Kobylkevich, Brian M.; Benson, Austin C.; Bruening, Kristi S.; Shribak, Michael; Rosenthal, Joshua J. C.; Sohn, Joel J. (University of Chicago Press, 2019-07-08)
    The pen, or gladius, of the squid is an internalized shell. It serves as a site of attachment for important muscle groups and as a protective barrier for the visceral organs. The pen’s durability and flexibility are derived ...
  • A composition-dependent molecular clutch between T cell signaling condensates and actin 

    Ditlev, Jonathon; Vega, Anthony R; Köster, Darius Vasco; Su, Xiaolei; Tani, Tomomi; Lakoduk, Ashley M; Vale, Ronald D.; Mayor, Satyajit; Jaqaman, Khuloud; Rosen, Michael K. (eLife Sciences Publications, 2019-07-03)
    During T cell activation, biomolecular condensates form at the immunological synapse (IS) through multivalency-driven phase separation of LAT, Grb2, Sos1, SLP-76, Nck, and WASP. These condensates move radially at the IS, ...

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