Molecular evolution of the membrane associated progesterone receptor in the Brachionus plicatilis (Rotifera, Monogononta) species complex
Molecular evolution of the membrane associated progesterone receptor in the Brachionus plicatilis (Rotifera, Monogononta) species complex
Date
2010-10
Authors
Smith, Hilary A.
Mark Welch, David B.
Snell, Terry W.
Mark Welch, David B.
Snell, Terry W.
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Keywords
dN/dS
Gene tree
PGRMC1
Protein structure
Signaling
Substitution
Gene tree
PGRMC1
Protein structure
Signaling
Substitution
Abstract
Many studies have investigated physiological roles of the membrane associated progesterone
receptor (MAPR), but little is known of its evolution. Marked variations in response to
exogenous progesterone have been reported for four brachionid rotifer species, suggesting
differences in progesterone signaling and reception. Here we report sequence variation for the
MAPR gene in the Brachionus plicatilis species complex. Phylogenetic analysis of this receptor
is compared with relatedness based on cytochrome c oxidase subunit 1 sequences.
Nonsynonymous to synonymous site substitution rate ratios, amino acid divergence, and
variations in predicted phosphorylation sites are examined to assess evolution of the MAPR
among brachionid clades.
Description
Author Posting. © Springer, 2010. This is the author's version of the work. It is posted here by permission of Springer for personal use, not for redistribution. The definitive version was published in Hydrobiologia 662 (2011): 99-106, doi:10.1007/s10750-010-0484-4.