Abu-Daya Anita

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Abu-Daya
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Anita
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  • Book chapter
    Advances in genome editing tools
    (Taylor & Francis, 2022-04-19) Horb, Marko E. ; Abu-Daya, Anita ; Wlizla, Marcin ; Noble, Anna ; Guille, Matthew
    This book focuses on the amphibian, Xenopus, one of the most commonly used model animals in the biological sciences. Over the past 50 years, the use of Xenopus has made possible many fundamental contributions to our knowledge in cell biology, developmental biology, molecular biology, and neurobiology. In recent years, with the completion of the genome sequence of the main two species and the application of genome editing techniques, Xenopus has emerged as a powerful system to study fundamental disease mechanisms and test treatment possibilities. Xenopus has proven an essential vertebrate model system for understanding fundamental cell and developmental biological mechanisms, for applying fundamental knowledge to pathological processes, for deciphering the function of human disease genes, and for understanding genome evolution. Key Features Provides historical context of the contributions of the model system Includes contributions from an international team of leading scholars Presents topics spanning cell biology, developmental biology, genomics, and disease model Describes recent experimental advances Incorporates richly illustrated diagrams and color images
  • Article
    Xenopus resources: Transgenic, inbred and mutant animals, training opportunities, and web-based support.
    (Frontiers Media, 2019-04-25) Horb, Marko E. ; Wlizla, Marcin ; Abu-Daya, Anita ; McNamara, Sean ; Gajdasik, Dominika ; Igawa, Takeshi ; Suzuki, Atsushi ; Ogino, Hajime ; Noble, Anna ; Robert, Jacques ; James-Zorn, Christina ; Guille, Matthew ; Nicolas, Morgane ; Lafond, Thomas ; Boujard, Daniel ; Audic, Yann ; Guillet, Brigitte ; Centre de Ressource Biologique Xenope team in France
    Two species of the clawed frog family, Xenopus laevis and X. tropicalis, are widely used as tools to investigate both normal and disease-state biochemistry, genetics, cell biology, and developmental biology. To support both frog specialist and non-specialist scientists needing access to these models for their research, a number of centralized resources exist around the world. These include centers that hold live and frozen stocks of transgenic, inbred and mutant animals and centers that hold molecular resources. This infrastructure is supported by a model organism database. Here, we describe much of this infrastructure and encourage the community to make the best use of it and to guide the resource centers in developing new lines and libraries.