Wang Bin

No Thumbnail Available
Last Name
Wang
First Name
Bin
ORCID

Filters

2016 - 2019 2 2020 - 2024 1
3
3
Reset filters

Settings

Search Results

Now showing 1 - 3 of 3
  • Article
    Global in situ observations of essential climate and ocean variables at the air-sea interface
    (Frontiers Media, 2019-07-25) Centurioni, Luca R. ; Turton, Jon ; Lumpkin, Rick ; Braasch, Lancelot ; Brassington, Gary ; Chao, Yi ; Charpentier, Etienne ; Chen, Zhaohui ; Corlett, Gary ; Dohan, Kathleen ; Donlon, Craig ; Gallage, Champika ; Hormann, Verena ; Ignatov, Alexander ; Ingleby, Bruce ; Jensen, Robert ; Kelly-Gerreyn, Boris A. ; Koszalka, Inga M. ; Lin, Xiaopei ; Lindstrom, Eric ; Maximenko, Nikolai ; Merchant, Christopher J. ; Minnett, Peter J. ; O’Carroll, Anne ; Paluszkiewicz, Theresa ; Poli, Paul ; Poulain, Pierre Marie ; Reverdin, Gilles ; Sun, Xiujun ; Swail, Val ; Thurston, Sidney ; Wu, Lixin ; Yu, Lisan ; Wang, Bin ; Zhang, Dongxiao
    The air–sea interface is a key gateway in the Earth system. It is where the atmosphere sets the ocean in motion, climate/weather-relevant air–sea processes occur, and pollutants (i.e., plastic, anthropogenic carbon dioxide, radioactive/chemical waste) enter the sea. Hence, accurate estimates and forecasts of physical and biogeochemical processes at this interface are critical for sustainable blue economy planning, growth, and disaster mitigation. Such estimates and forecasts rely on accurate and integrated in situ and satellite surface observations. High-impact uses of ocean surface observations of essential ocean/climate variables (EOVs/ECVs) include (1) assimilation into/validation of weather, ocean, and climate forecast models to improve their skill, impact, and value; (2) ocean physics studies (i.e., heat, momentum, freshwater, and biogeochemical air–sea fluxes) to further our understanding and parameterization of air–sea processes; and (3) calibration and validation of satellite ocean products (i.e., currents, temperature, salinity, sea level, ocean color, wind, and waves). We review strengths and limitations, impacts, and sustainability of in situ ocean surface observations of several ECVs and EOVs. We draw a 10-year vision of the global ocean surface observing network for improved synergy and integration with other observing systems (e.g., satellites), for modeling/forecast efforts, and for a better ocean observing governance. The context is both the applications listed above and the guidelines of frameworks such as the Global Ocean Observing System (GOOS) and Global Climate Observing System (GCOS) (both co-sponsored by the Intergovernmental Oceanographic Commission of UNESCO, IOC–UNESCO; the World Meteorological Organization, WMO; the United Nations Environment Programme, UNEP; and the International Science Council, ISC). Networks of multiparametric platforms, such as the global drifter array, offer opportunities for new and improved in situ observations. Advances in sensor technology (e.g., low-cost wave sensors), high-throughput communications, evolving cyberinfrastructures, and data information systems with potential to improve the scope, efficiency, integration, and sustainability of the ocean surface observing system are explored.
  • Article
    HIV glycoprotein Gp120 impairs fast axonal transport by activating Tak1 signaling pathways
    (Sage, 2016-11-01) Berth, Sarah ; Mesnard-Hoaglin, Nichole ; Wang, Bin ; Kim, Hajwa ; Song, Yuyu ; Sapar, Maria ; Morfini, Gerardo A. ; Brady, Scott T.
    Sensory neuropathies are the most common neurological complication of HIV. Of these, distal sensory polyneuropathy (DSP) is directly caused by HIV infection and characterized by length-dependent axonal degeneration of dorsal root ganglion (DRG) neurons. Mechanisms for axonal degeneration in DSP remain unclear, but recent experiments revealed that the HIV glycoprotein gp120 is internalized and localized within axons of DRG neurons. Based on these findings, we investigated whether intra-axonal gp120 might impair fast axonal transport (FAT), a cellular process critical for appropriate maintenance of the axonal compartment. Significantly, we found that gp120 severely impaired both anterograde and retrograde FAT. Providing a mechanistic basis for these effects, pharmacological experiments revealed an involvement of various phosphotransferases in this toxic effect, including members of mitogen-activated protein kinase pathways (Tak-1, p38, and c-Jun N-terminal Kinase (JNK)), inhibitor of kappa-B-kinase 2 (IKK2), and PP1. Biochemical experiments and axonal outgrowth assays in cell lines and primary cultures extended these findings. Impairments in neurite outgrowth in DRG neurons by gp120 were rescued using a Tak-1 inhibitor, implicating a Tak-1 mitogen-activated protein kinase pathway in gp120 neurotoxicity. Taken together, these observations indicate that kinase-based impairments in FAT represent a novel mechanism underlying gp120 neurotoxicity consistent with the dying-back degeneration seen in DSP. Targeting gp120-based impairments in FAT with specific kinase inhibitors might provide a novel therapeutic strategy to prevent axonal degeneration in DSP.
  • Article
    Fast reduction of Atlantic SST threatens Europe-wide gross primary productivity under positive and negative CO2 emissions
    (Wiley, 2024-06-01) Yang, Young-Min ; Shin, Jongsoo ; Park, So-Won ; Park, Jae-Heung ; An, Soon-Il ; Kug, Jong-Seong ; Yeh, Sang-Wook ; Lee, June-Yi ; Wang, Bin ; Li, Tim ; Im, Nari
    Climate change mitigation through negative CO2 emissions has been recognized as a crucial strategy to combat global warming. However, its potential effects on terrestrial productivity and agricultural activities remain uncertain. In this study, we utilized large ensemble simulations with an Earth system model of full complexity to investigate the response of Gross Primary Production (GPP) to CO2 forcings. Our findings reveal a significant asymmetry in the GPP response to CO2 ramp-up and symmetric ramp-down model experiments, especially in Europe, suggesting that GPP declines rapidly as CO2 levels decrease. Remarkably, during the CO2 removal period, the North Atlantic Sea surface temperature experienced cooling due to a delayed recovery of the Atlantic Meridional Overturning Circulation (AMOC). This cooling led to precipitation and soil moisture deficits, resulting in a rapid reduction in GPP. This asymmetry in GPP response holds consistent across multi-model simulations. These results underscore the potential implications of delayed recovery in ocean circulation, which could unexpectedly accelerate terrestrial GPP reduction. These insights are crucial for policymakers, aiding them in projecting agricultural activity and formulating targeted GPP control policies specific to the European region.