Toxics source reduction and sewage upgrades eliminated winter flounder liver neoplasia (1984-2017) from Boston Harbor, MA, USA
Moore, Michael J.
MetadataShow full item record
Chemical carcinogen biomarkers can validate public investment in environmental remediation. A major factor driving the clean-up of Boston Harbor, MA, USA, induced by the federal Clean Water Act legislation of 1972, was the high prevalence of petroleum and halogenated aromatic hydrocarbon contaminant-associated liver neoplasia in winter flounder Pseudopleuronectes americanus in the harbor in the 1980s. In the present study, we examined the spatial and temporal relationships between the suspended solids and contaminants in the municipal sewage discharge, and liver neoplasia and histopathology in flounder, from 1987 to 2017. Toxics source reduction, sewage treatment, and sludge removal in the 1990s and outfall relocation offshore in 2000 enabled a decreasing prevalence of persistent toxic chemicals in flounder, effluent, and sediment, and consequent disappearance of liver neoplasia and reduction of neoplasm-associated, hydropically vacuolated biliary epithelial cells to background levels. This supports long-term investment in elimination and treatment of anthropogenic waste streams and the value of federal regulatory mandates to maintain and improve regional environmental quality.
© The Author(s), 2018. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Diseases of Aquatic Organisms 131 (2018) 239-243, doi:10.3354/dao03299.
Suggested CitationDiseases of Aquatic Organisms 131 (2018) 239-243
The following license files are associated with this item:
Showing items related by title, author, creator and subject.
Vacuolation, proliferation and neoplasia in the liver of Boston Harbor winter flounder (Pseudopleuronectes americanus) Moore, Michael J. (Massachusetts Institute of Technology and Woods Hole Oceanographic Institution, 1991-07)Neoplasia has been found in the livers of bottom-feeding fish taken from heavily contaminated freshwater and marine habitats. This study examined the progressive development and ultimate diversity of liver neoplasia in ...
Response of benthic metabolism and nutrient cycling to reductions in wastewater loading to Boston Harbor, USA Tucker, Jane; Giblin, Anne E.; Hopkinson, Charles S.; Kelsey, Samuel W.; Howes, Brian L. (Elsevier, 2014-10-02)We describe the long-term response of benthic metabolism in depositional sediments of Boston Harbor, MA, to large reductions in organic matter and nutrient loading. Although Boston Harbor received very high loadings of ...
Changeable camouflage : how well can flounder resemble the colour and spatial scale of substrates in their natural habitats? Akkaynak, Derya; Siemann, Liese A.; Barbosa, Alexandra; Mathger, Lydia M. (Royal Society, 2017-03-08)Flounder change colour and pattern for camouflage. We used a spectrometer to measure reflectance spectra and a digital camera to capture body patterns of two flounder species camouflaged on four natural backgrounds of ...