The binder cometh! Or, the story of the librarian and the library binder
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The amino terminus of tau inhibits kinesin-dependent axonal transport: Implications for filament toxicity LaPointe, Nichole E.; Morfini, Gerardo A.; Pigino, Gustavo F.; Gaisina, Irina N.; Kozikowski, Alan P.; Binder, Lester I.; Brady, Scott T. (2008-04)The neuropathology of Alzheimer’s disease (AD) and other tauopathies is characterized by filamentous deposits of the microtubule-associated protein tau, but the relationship between tau polymerization and neurotoxicity ...
Xenobiotic monooxygenase activity and the response to inducers of cytochrome P-450 during embryonic and larval development in fish Binder, Robert L. (Massachusetts Institute of Technology and Woods Hole Oceanographic Institution, 1981-08)Data demonstrating the presence and inducibility of the xenobiotic monooxygenase system in fish embryos and larvae are described. The ontogeny of benzo(a)pyrene monooxygenase (BPM) activity, and NADPH- and NADH-cytochrome ...
Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases Kanaan, Nicholas M.; Morfini, Gerardo A.; LaPointe, Nichole E.; Pigino, Gustavo F.; Patterson, Kristina R.; Song, Yuyu; Andreadis, Athena; Fu, Yifan; Brady, Scott T.; Binder, Lester I. (Society for Neuroscience, 2011-07-06)Aggregated filamentous forms of hyperphosphorylated tau (a microtubule-associated protein) represent pathological hallmarks of Alzheimer's disease (AD) and other tauopathies. While axonal transport dysfunction is thought ...