Introducing the microbiome into Precision Medicine
Date
2016-11Metadata
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https://hdl.handle.net/1912/8738As published
https://doi.org/10.1016/j.tips.2016.10.001Abstract
Understanding how individual people respond to medical therapy is a key facet of improving the odds ratio that interventions will have a positive impact. Reducing the non-responder rate for an intervention or reducing complications associated with a particular treatment or surgery is the next stage of medical advance. The Precision Medicine Initiative, launched in January 2015, set the stage for enhanced collaboration between researchers and medical professionals to develop next-generation techniques to aid patient treatment and recovery, and increased the opportunities for impactful pre-emptive care. The microbiome plays a crucial role in health and disease, as it influences endocrinology, physiology, and even neurology, altering the outcome of many different disease states, and it augments drug responses and tolerance. We review the implications of the microbiome on precision health initiatives and highlight excellent examples, whereby precision microbiome health has been implemented.
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© The Author(s), 2016. This is the author's version of the work and is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Trends in Pharmacological Sciences 38 (2017): 81-91, doi:10.1016/j.tips.2016.10.001.
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Preprint: Kuntz, Thomas M., Gilbert, Jack A., "Introducing the microbiome into Precision Medicine", 2016-11, https://doi.org/10.1016/j.tips.2016.10.001, https://hdl.handle.net/1912/8738The following license files are associated with this item: