Integrating monitoring and genetic methods to infer historical risks of PCBs and DDE to common and roseate terns nesting near the New Bedford Harbor Superfund site (Massachusetts, USA)
Nacci, Diane E.
Hahn, Mark E.
Karchner, Sibel I.
Miller, Kenneth M.
Blackwell, Carma Gilchrist
Nisbet, Ian C. T.
MetadataShow full item record
Common and roseate terns are migratory piscivorous seabirds with major breeding colonies within feeding range of the PCB-contaminated New Bedford Harbor (NBH, MA, USA) Superfund site. Our longitudinal study shows that before PCB discharges into NBH ceased (late 1970s), tern eggs had very high but variable PCB concentrations. But egg concentrations of PCBs as well as DDE, the degradation product of the ubiquitous global contaminant DDT, have since declined. Rate constants for temporal decline of PCB congeners in tern eggs varied inversely with log10KOW (n-octanol-water partition coefficient), shifting egg congener patterns away from those characterizing NBH sediment. To estimate the toxic effects on tern eggs of PCB dioxin-like congener (DLC) exposures, we extrapolated published laboratory data on common terns to roseate terns by characterizing genetic and functional similarities in species aryl-hydrocarbon receptors (AHRs), which mediate DLC sensitivity. Our assessment of contaminant risks suggests that terns breeding near NBH were exposed historically to toxic levels of PCBs and DDE; however, acute effects on tern egg development have become less likely since the 1970s. Our approach demonstrates how comparative genetics at target loci can effectively increase the range of inference for chemical risk assessments from tested to untested and untestable species.
Author Posting. © The Author(s), 2016. This is the author's version of the work. It is posted here by permission of American Chemical Society for personal use, not for redistribution. The definitive version was published in Environmental Science & Technology 50 (2016): 10226–10235, doi:10.1021/acs.est.6b02108.
Suggested CitationPreprint: Nacci, Diane E., Hahn, Mark E., Karchner, Sibel I., Jayaraman, Saro, Mostello, Carolyn, Miller, Kenneth M., Blackwell, Carma Gilchrist, Nisbet, Ian C. T., "Integrating monitoring and genetic methods to infer historical risks of PCBs and DDE to common and roseate terns nesting near the New Bedford Harbor Superfund site (Massachusetts, USA)", 2016-09, https://doi.org/10.1021/acs.est.6b02108, https://hdl.handle.net/1912/8497
Showing items related by title, author, creator and subject.
Geyer, W. Rockwell; Dragos, Paul (Woods Hole Oceanographic Institution, 1990-12)Thls report includes a compilation of hydrodynamic data obtained in New Bedford Harbor, Massachusetts (Figue 1-1), for the purpose of providing baseline information for the selection of an outfall site for a seondary ...
Expression and function of ryanodine receptor related pathways in PCB tolerant Atlantic killifish (Fundulus heteroclitus) from New Bedford Harbor, MA, USA Fritsch, Erika B.; Stegeman, John J.; Goldstone, Jared V.; Nacci, Diane E.; Champlin, Denise; Jayaraman, Saro; Connon, Richard E.; Pessah, Isaac N. (2014-12)Atlantic killifish (Fundulus heteroclitus) thrive in New Bedford Harbor (NBH), MA, highly contaminated with polychlorinated biphenyls (PCBs). Resident killifish have evolved tolerance to dioxin-like (DL) PCBs, whose toxic ...
Waterfront land use change and marine resource conditions : the case of New Bedford and Fairhaven, Massachusetts Portman, Michelle E.; Jin, Di; Thunberg, Eric M. (2009-03)A major challenge in gauging long-term and cumulative impacts of fisheries management on coastal fishing communities is the lack of understanding of the interactions between changes in fish stocks and waterfront land ...