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dc.contributor.authorZozaya, Marcela  Concept link
dc.contributor.authorFerris, Michael J.  Concept link
dc.contributor.authorSiren, Julia D.  Concept link
dc.contributor.authorLillis, Rebecca  Concept link
dc.contributor.authorMyers, Leann  Concept link
dc.contributor.authorNsuami, M. Jacques  Concept link
dc.contributor.authorEren, A. Murat  Concept link
dc.contributor.authorBrown, Jonathan  Concept link
dc.contributor.authorTaylor, Christopher M.  Concept link
dc.contributor.authorMartin, David H.  Concept link
dc.identifier.citationMicrobiome 4 (2016): 16en_US
dc.description© The Author(s), 2016. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Microbiome 4 (2016): 16, doi:10.1186/s40168-016-0161-6.en_US
dc.description.abstractThe epidemiology of bacterial vaginosis (BV) suggests it is sexually transmissible, yet no transmissible agent has been identified. It is probable that BV-associated bacterial communities are transferred from male to female partners during intercourse; however, the microbiota of sexual partners has not been well-studied. Pyrosequencing analysis of PCR-amplified 16S rDNA was used to examine BV-associated bacteria in monogamous couples with and without BV using vaginal, male urethral, and penile skin specimens. The penile skin and urethral microbiota of male partners of women with BV was significantly more similar to the vaginal microbiota of their female partner compared to the vaginal microbiota of non-partner women with BV. This was not the case for male partners of women with normal vaginal microbiota. Specific BV-associated species were concordant in women with BV and their male partners. In monogamous heterosexual couples in which the woman has BV, the significantly higher similarity between the vaginal microbiota and the penile skin and urethral microbiota of the male partner, supports the hypothesis that sexual exchange of BV-associated bacterial taxa is common.en_US
dc.description.sponsorshipThis work was supported by National Institute of Health Grant R01 AI079071-01A1.en_US
dc.publisherBioMed Centralen_US
dc.rightsAttribution 4.0 International
dc.subjectBacterial vaginosisen_US
dc.subjectSexual transmissionen_US
dc.subjectPenile skinen_US
dc.titleBacterial communities in penile skin, male urethra, and vaginas of heterosexual couples with and without bacterial vaginosisen_US

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Attribution 4.0 International
Except where otherwise noted, this item's license is described as Attribution 4.0 International