Now showing items 1-3 of 3

    • Mammalian end binding proteins control persistent microtubule growth 

      Komarova, Yulia A.; De Groot, Christian O.; Grigoriev, Ilya; Gouveia, Susana Montenegro; Munteanu, E. Laura; Schober, Joseph M.; Honnappa, Srinivas; Buey, Ruben M.; Hoogenraad, Casper C.; Dogterom, Marileen; Borisy, Gary G.; Steinmetz, Michel O.; Akhmanova, Anna (Rockefeller University Press, 2009-03-02)
      End binding proteins (EBs) are highly conserved core components of microtubule plus-end tracking protein networks. Here we investigated the roles of the three mammalian EBs in controlling microtubule dynamics and analyzed ...
    • Migration and actin protrusion in melanoma cells are regulated by EB1 protein 

      Schober, Joseph M.; Cain, Jeanine M.; Komarova, Yulia A.; Borisy, Gary G. (2009-04)
      Remodeling of actin and microtubule cytoskeletons is thought to be coupled; however, the interplay between these two systems is not fully understood. We show a microtubule end-binding protein, EB1, is required for formation ...
    • Phosphorylation controls autoinhibition of cytoplasmic linker protein-170 

      Lee, Ho-Sup; Komarova, Yulia A.; Nadezhdina, Elena S.; Anjum, Rana; Peloquin, John G.; Schober, Joseph M.; Danciu, Oana; van Haren, Jeffrey; Galjart, Niels; Gygi, Steven P.; Akhmanova, Anna; Borisy, Gary G. (American Society for Cell Biology, 2010-06-02)
      Cytoplasmic linker protein (CLIP)-170 is a microtubule (MT) plus-end-tracking protein that regulates MT dynamics and links MT plus ends to different intracellular structures. We have shown previously that intramolecular ...