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dc.contributor.authorPerry, D. Alexander  Concept link
dc.contributor.authorMorrison, Hilary G.  Concept link
dc.contributor.authorAdam, Rodney D.  Concept link
dc.date.accessioned2012-02-27T20:04:10Z
dc.date.available2012-02-27T20:04:10Z
dc.date.issued2011-07
dc.identifier.urihttps://hdl.handle.net/1912/5050
dc.descriptionAuthor Posting. © The Author(s), 2011. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Molecular and Biochemical Parasitology 180 (2011): 112-114, doi:10.1016/j.molbiopara.2011.07.008.en_US
dc.description.abstractThe Giardia lamblia genome consists of 12 Mb divided among 5 chromosomes ranging in size from approximately 1 to 4 Mb. The assembled contigs of the genotype A1 isolate, WB, were previously mapped along the 5 chromosomes on the basis of hybridization of plasmid clones representing the contigs to chromosomes separated by PFGE. In the current report, we have generated an MluI optical map of the WB genome to improve the accuracy of the physical map. This has allowed us to correct several assembly errors and to better define the extent of the subtelomeric regions that are not included in the genome assembly.en_US
dc.description.sponsorshipThis work was funded in part by the Woods Hole Center for Oceans and Human Health, jointly funded by the National Science Foundation (OCE-0430724) and the National Institute for Environmental Health Sciences (P50 ES012742).en_US
dc.format.mimetypeapplication/pdf
dc.format.mimetypeapplication/vnd.ms-excel
dc.language.isoen_USen_US
dc.relation.urihttps://doi.org/10.1016/j.molbiopara.2011.07.008
dc.subjectOptical mapen_US
dc.subjectGenomeen_US
dc.subjectPulsed field gel electrophoresisen_US
dc.subjectSubtelomeric variationen_US
dc.titleOptical map of the genotype A1 WB C6 Giardia lamblia genome isolateen_US
dc.typePreprinten_US


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