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The tunicate Ciona : a model system for understanding the relationship between regeneration and aging
(Taylor & Francis, 2014-06-10)
The use of the tunicate Ciona intestinalis as a model system to study the relationship between regeneration and aging is reviewed. Ciona has powerful regeneration capacities, which fade with age. Some additional benefits ...
Employing BAC-reporter constructs in the sea anemone Nematostella vectensis
Changes in the expression and function of genes drive evolutionary change. Comparing how genes are regulated in different species is therefore becoming an important part of evo-devo studies. A key tool for investigating ...
Formation of the statolith in the ctenophore Mnemiopsis leidyi
(Marine Biological Laboratory, 2014-08-01)
The aboral sensory organ (apical organ) of ctenophores contains a statocyst with a single large statolith. The statolith comprises living cells (lithocytes), each containing a large membrane-bound concretion. The statolith ...
Meeting report of Ctenopalooza : the first international meeting of ctenophorologists
(BioMed Central, 2016-08-25)
Here we present a report on Ctenopalooza: A meeting of ctenophorologists held at the Whitney Laboratory for Marine Bioscience in St. Augustine, FL, USA, on March 14–15, 2016. In this report, we provide a summary of each ...
Acute increase of α-synuclein inhibits synaptic vesicle recycling evoked during intense stimulation
(American Society for Cell Biology, 2014-10-01)
Parkinson's disease is associated with multiplication of the α-synuclein gene and abnormal accumulation of the protein. In animal models, α-synuclein overexpression broadly impairs synaptic vesicle trafficking. However, ...
Expression and reconstitution of the bioluminescent Ca2+ reporter aequorin in human embryonic stem cells, and exploration of the presence of functional IP3 and ryanodine receptors during the early stages of their differentiation into cardiomyocytes
In order to develop a novel method of visualizing possible Ca2+ signaling during the early differentiation of hESCs into cardiomyocytes and avoid some of the inherent problems associated with using fluorescent reporters, ...
Distal regeneration involves the age dependent activity of branchial sac stem cells in the ascidian Ciona intestinalis
(John Wiley & Sons, 2014-11-13)
Tunicates have high capacities for regeneration but the underlying mechanisms and their relationship to life cycle progression are not well understood. Here we investigate the regeneration of distal structures in the ...
Genome-wide identification of enhancer elements
(UPV/EHU Press, 2016-06)
We present a prospective genome-wide regulatory element database for the sea urchin embryo and the modified chromosome capture-related methodology used to create it. The method we developed is termed GRIP-seq for genome-wide ...