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An optimized method for cryogenic storage of Xenopus sperm to maximise the effectiveness of research using genetically altered frogs
Cryogenic storage of sperm from genetically altered Xenopus improves cost effectiveness and animal welfare associated with their use in research; currently it is routine for X. tropicalis but not reliable for X. laevis. ...
A novel interception strategy in a miniature robber fly with extreme visual acuity
(Cell Press, 2017-03-09)
Our visual system allows us to rapidly identify and intercept a moving object. When this object is far away, we base the trajectory on the target’s location relative to an external frame of reference . This process forms ...
Mutations underlying Episodic Ataxia type-1 antagonize Kv1.1 RNA editing
(Nature Publishing Group, 2017-02-20)
Adenosine-to-inosine RNA editing in transcripts encoding the voltage-gated potassium channel Kv1.1 converts an isoleucine to valine codon for amino acid 400, speeding channel recovery from inactivation. Numerous Kv1.1 ...
Transcriptomic insights into genetic diversity of protein-coding genes in X. laevis
We characterize the genetic diversity of Xenopus laevis strains using RNA-seq data and allele- specific analysis. This data provides a catalogue of coding variation, which can be used for improving the genomic sequence, ...
Target detection in insects : optical, neural and behavioral optimizations
Motion vision provides important cues for many tasks. Flying insects, for example, may pursue small, fast moving targets for mating or feeding purposes, even when these are detected against self-generated optic flow. Since ...
Changeable camouflage : how well can flounder resemble the colour and spatial scale of substrates in their natural habitats?
(Royal Society, 2017-03-08)
Flounder change colour and pattern for camouflage. We used a spectrometer to measure reflectance spectra and a digital camera to capture body patterns of two flounder species camouflaged on four natural backgrounds of ...
Generation of a Xenopus laevis F1 albino J strain by genome editing and oocyte host-transfer
Completion of the Xenopus laevis genome sequence from inbred J strain animals has facilitated the generation of germline mutant X. laevis using targeted genome editing. In the last few years, numerous reports have demonstrated ...
Luteinizing Hormone is an effective replacement for hCG to induce ovulation in Xenopus
Injection of human Chorionic Gonadotropin (hCG) directly into the dorsal lymph sac of Xenopus is a commonly used protocol for induction of ovulation, but recent shortages in the stocks of commercially available hCG as well ...