Now showing items 1-20 of 8810

    • Contribution of increasing plasma membrane to the energetic cost of early zebrafish embryogenesis 

      Rodenfels, Jonathan; Sartori, Pablo; Golfier, Stefan; Nagendra, Kartikeya; Neugebauer, Karla M.; Howard, Jonathon (American Society for Cell Biology, 2020-03-19)
      How do early embryos allocate the resources stored in the sperm and egg? Recently, we established isothermal calorimetry to measure heat dissipation by living zebra­fish embryos and to estimate the energetics of specific ...
    • Hydrocarbon seepage in the deep seabed links subsurface and seafloor biospheres 

      Chakraborty, Anirban; Ruff, S. Emil; Dong, Xiyang; Ellefson, Emily D.; Li, Carmen; Brooks, James M.; McBee, Jayme; Bernard, Bernie B.; Hubert, Casey R. J. (National Academy of Sciences, 2020-04-30)
      Marine cold seeps transmit fluids between the subseafloor and seafloor biospheres through upward migration of hydrocarbons that originate in deep sediment layers. It remains unclear how geofluids influence the composition ...
    • Buzzards Bay Water Quality Data from the Buzzards Bay Coalition’s Baywatchers Program 1992-2018 

      Jakuba, Rachel W.; Williams, Tony; Neill, Christopher; Costa, Joseph E.; McHorney, Richard; Scott, Lindsay; Howes, Brian L.; Ducklow, Hugh W.; Erickson, Matthew; Rasmussen, Mark (Woods Hole Oceanographic Institution, 2020-05-04)
      The Buzzards Bay Coalition’s Baywatchers Monitoring Program collected summertime water quality information at more than 150 stations around Buzzards Bay, Massachusetts from 1992 to 2018. Baywatchers monitoring data document ...
    • An approach to modeling resource optimization for substitutable and interdependent resources 

      Rastetter, Edward B.; Kwiatkowski, Bonnie L. (Elsevier, 2020-03-31)
      We develop a hierarchical approach to modeling organism acclimation to changing availability of and requirements for substitutable and interdependent resources. Substitutable resources are resources that fill the same ...
    • Radial alignment of microtubules through tubulin polymerization in an evaporating droplet 

      Keya, Jakia Jannat; Kudoh, Hiroki; Kabir, Arif Md. Rashedul; Inoue, Daisuke; Miyamoto, Nobuyoshi; Tani, Tomomi; Kakugo, Akira; Shikinaka, Kazuhiro (Public Library of Science, 2020-04-10)
      We report the formation of spherulites from droplets of highly concentrated tubulin solution via nucleation and subsequent polymerization to microtubules (MTs) under water evaporation by heating. Radial alignment of MTs ...
    • Electrophysiological and motor responses to chemosensory stimuli in isolated cephalopod arms 

      Fouke, Kaitlyn E.; Rhodes, Heather J. (University of Chicago Press, 2020-02-17)
      While there is behavioral and anatomical evidence that coleoid cephalopods use their arms to “taste” substances in the environment, the neurophysiology of chemosensation has been largely unexamined. The range and sensitivity ...
    • Spatially regulated editing of genetic information within a neuron 

      Vallecillo-Viejo, Isabel C.; Liscovitch-Brauer, Noa; Diaz Quiroz, Juan F.; Montiel-González, Maria Fernanda; Nemes, Sonya E.; Rangan, Kavita J.; Levinson, Simon R.; Eisenberg, Eli; Rosenthal, Joshua J. C. (Oxford University Press, 2020-03-23)
      In eukaryotic cells, with the exception of the specialized genomes of mitochondria and plastids, all genetic information is sequestered within the nucleus. This arrangement imposes constraints on how the information can ...
    • FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells 

      Smith, Jean A.; Curry, Ennessa G.; Blue, R. Eric; Roden, Christine; Dundon, Samantha E.R.; Rodríguez-Vargas, Anthony; Jordan, Danielle C.; Chen, Xiaomin; Lyons, Shawn M.; Crutchley, John M.; Anderson, Paul; Horb, Marko E.; Gladfelter, Amy S.; Giudice, Jimena (Rockefeller University Press, 2020-03-13)
      Fragile-X mental retardation autosomal homologue-1 (FXR1) is a muscle-enriched RNA-binding protein. FXR1 depletion is perinatally lethal in mice, Xenopus, and zebrafish; however, the mechanisms driving these phenotypes ...
    • Evaluation of simulated soil carbon dynamics in Arctic-Boreal ecosystems 

      Huntzinger, Deborah N.; Schaefer, Kevin; Schwalm, Christopher R.; Fisher, Joshua B.; Hayes, Daniel; Stofferahn, Eric; Carey, Joanna C.; Michalak, Anna M.; Wei, Yaxing; Jain, Atul K.; Kolus, Hannah; Mao, Jiafu; Poulter, Benjamin; Shi, Xiaoying; Tang, Jianwu; Tian, Hanqin (IOP Publishing, 2020-02-07)
      Given the magnitude of soil carbon stocks in northern ecosystems, and the vulnerability of these stocks to climate warming, land surface models must accurately represent soil carbon dynamics in these regions. We evaluate ...
    • Resegmentation is an ancestral feature of the gnathostome vertebral skeleton 

      Criswell, Katharine E.; Gillis, J. Andrew (eLife Sciences Publications, 2020-02-24)
      The vertebral skeleton is a defining feature of vertebrate animals. However, the mode of vertebral segmentation varies considerably between major lineages. In tetrapods, adjacent somite halves recombine to form a single ...
    • Extraction of high-quality, high-molecular-weight DNA depends heavily on cell homogenization methods in green microalgae 

      Stark, Jordan R.; Cardon, Zoe G.; Peredo, Elena L. (Wiley Open Access, 2020-03-10)
      Premise New sequencing technologies have facilitated genomic studies in green microalgae; however, extracting high‐quality DNA is often a bottleneck for long‐read sequencing. Methods and Results Here, we present ...
    • Synaptic actions of amyotrophic-lateral-sclerosis-associated G85R-SOD1 in the squid giant synapse 

      Song, Yuyu (Society for Neuroscience, 2020-03-18)
      Altered synaptic function is thought to play a role in many neurodegenerative diseases, but little is known about the underlying mechanisms for synaptic dysfunction. The squid giant synapse (SGS) is a classical model for ...
    • Unraveling spatiotemporal variability of arbuscular mycorrhizal fungi in a temperate grassland plot 

      Goldmann, Kezia; Boeddinghaus, Runa S.; Klemmer, Sandra; Regan, Kathleen M.; Heintz‐Buschart, Anna; Fischer, Markus; Prati, Daniel; Piepho, Hans‐Peter; Berner, Doreen; Marhan, Sven; Kandeler, Ellen; Buscot, François; Wubet, Tesfaye (Wiley, 2019-03-14)
      Soils provide a heterogeneous environment varying in space and time; consequently, the biodiversity of soil microorganisms also differs spatially and temporally. For soil microbes tightly associated with plant roots, such ...
    • Absolute proteomic quantification reveals design principles of sperm flagellar chemosensation 

      Trotschel, Christian; Hamzeh, Hussein; Alvarez, Luis; Pascal, René; Lavryk, Fedir; Bönigk, Wolfgang; Körschen, Heinz Gerd; Müller, Astrid; Poetsch, Ansgar; Rennhack, Andreas; Gui, Long; Nicastro, Daniela; Strünker, Timo; Seifert, Reinhard; Kaupp, U. Benjamin (EMBO Press, 2019-12-27)
      Cilia serve as cellular antennae that translate sensory information into physiological responses. In the sperm flagellum, a single chemoattractant molecule can trigger a Ca2+ rise that controls motility. The mechanisms ...
    • A de novo reference transcriptome for Bolitoglossa vallecula, an Andean mountain salamander in Colombia 

      Arenas Gómez, Claudia Marcela; Woodcock, M. Ryan; Smith, Jeramiah J.; Voss, S. Randal; Delgado, Jean Paul (Elsevier, 2020-02-11)
      The amphibian order Caudata, contains several important model species for biological research. However, there is need to generate transcriptome data from representative species of the primary salamander families. Here we ...
    • 12-h clock regulation of genetic information flow by XBP1s 

      Pan, Yinghong; Ballance, Heather; Meng, Huan; Gonzalez, Naomi; Kim, Sam-Moon; Abdurehman, Leymaan; York, Brian; Chen, Xi; Schnytzer, Yisrael; Levy, Oren; Dacso, Clifford C.; McClung, Colleen A.; O’Malley, Bert W.; Liu, Silvia; Zhu, Bokai (Public Library of Science, 2020-01-14)
      Our group recently characterized a cell-autonomous mammalian 12-h clock independent from the circadian clock, but its function and mechanism of regulation remain poorly understood. Here, we show that in mouse liver, ...
    • Methane oxidation and methylotroph population dynamics in groundwater mesocosms 

      Kuloyo, Olukayode; Ruff, S. Emil; Cahill, Aaron; Connors, Liam; Zorz, Jackie K.; Hrabe de Angelis, Isabella; Nightingale, Michael; Mayer, Bernhard; Strous, Marc (Wiley, 2020-02-03)
      Extraction of natural gas from unconventional hydrocarbon reservoirs by hydraulic fracturing raises concerns about methane migration into groundwater. Microbial methane oxidation can be a significant methane sink. Here, ...
    • The various routes to functional regeneration in the central nervous system 

      Echeverri, Karen (Nature Research, 2020-01-29)
      The axolotl is a type of Mexican salamander with astonishing regenerative capacity1. In our recent paper, we identified a signaling heterodimer that is formed directly after injury in the glial cells adjacent to the injury ...
    • Phosphorylation of nephrin induces phase separated domains that move through actomyosin contraction 

      Kim, Soyeon; Kalappurakkal, Joseph Mathew; Mayor, Satyajit; Rosen, Michael K. (American Society for Cell Biology, 2019-11-14)
      The plasma membrane of eukaryotic cells is organized into lipid and protein microdomains, whose assembly mechanisms and functions are incompletely understood. We demonstrate that proteins in the nephrin/Nck/N-WASP ...
    • A cerebellum-like circuit in the lateral line system of fish cancels mechanosensory input associated with its own movements 

      Perks, Krista E.; Krotinger, Anna; Bodznick, David (Company of Biologists, 2020-01-17)
      An animal's own movement exerts a profound impact on sensory input to its nervous system. Peripheral sensory receptors do not distinguish externally generated stimuli from stimuli generated by an animal's own behavior ...