Now showing items 191-200 of 984
The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase
(Oxford University Press, 2007-03-27)
Trypanosomatids contain an unusual DNA base J (ß-D-glucosylhydroxymethyluracil), which replaces a fraction of thymine in telomeric and other DNA repeats. To determine the function of base J, we have searched for enzymes ...
Length control of the metaphase spindle
The pole-to-pole distance of the metaphase spindle is reasonably constant in a given cell type; in the case of vertebrate female oocytes, this steady state length can be maintained for substantial lengths of time, during ...
Biogeography of bacterioplankton in lakes and streams of an arctic tundra catchment
(Ecological Society of America, 2007-06)
Bacterioplankton community composition was compared across 10 lakes and 14 streams within the catchment of Toolik Lake, a tundra lake in Arctic Alaska, during seven surveys conducted over three years using denaturing ...
Presynaptic nanodomains : a tale of two synapses
(Frontiers Media, 2015-01-26)
Here we summarize the evidence from two “giant” presynaptic terminals—the squid giant synapse and the mammalian calyx of Held—supporting the involvement of nanodomain calcium signals in triggering of neurotransmitter ...
Image analysis for biology
pH dependent isotropic to nematic phase transitions in graphene oxide dispersions reveal droplet liquid crystalline phases
Size fractionation, amplified by the surface charge density of graphene oxide (GO) sheets, broadens the pH dependent isotropic (I) to nematic (N) phase transition in aqueous dispersions of graphene oxide (GO). In this ...
Voltage-gated calcium channel subunits from platyhelminths : potential role in praziquantel action
Voltage-gated calcium (Ca2+) channels provide the pathway for Ca2+ influxes that underlie Ca2+-dependent responses in muscles, nerves, and other excitable cells. They are also targets of a wide variety of drugs and toxins. ...
Bryostatin enhancement of memory in Hermissenda
(Marine Biological Laboratory, 2006-06)
Bryostatin, a potent agonist of protein kinase C (PKC), when administered to Hermissenda was found to affect acquisition of an associative learning paradigm. Low bryostatin concentrations (0.1 to 0.5 ng/ml) enhanced memory ...
Laser microsurgery in the GFP era : a cell biologist's perspective
Modern biology is based largely on a reductionistic ‘dissection’ approach – most cell biologists try to determine how complex biological systems work by removing their individual parts and studying the effects of this ...
Sugars as source indicators of biogenic organic carbon in aerosols collected above the Howland Experimental Forest, Maine
Bulk aerosols (> 1 μm) were collected continuously above the canopy at the Howland Experimental Forest, Maine, USA from May to October 2002. Each sample integrated over an approximately two-week period. Mono- and ...