Now showing items 11-20 of 947
Spindle assembly in the absence of a RanGTP gradient requires localized CPC activity
During animal cell division, a gradient of GTP-bound Ran is generated around mitotic chromatin. It is generally accepted that this RanGTP gradient is essential for organizing the spindle since it locally activates critical ...
Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindles
(American Society for Cell Biology, 2005-03-23)
Metaphase spindles assemble to a steady state in length by mechanisms that involve microtubule dynamics and motor proteins, but they are incompletely understood. We found that Xenopus extract spindles recapitulate the ...
Microtubule plus-end dynamics in Xenopus egg extract spindles
(American Society for Cell Biology, 2004-02-06)
Microtubule dynamics underlie spindle assembly, yet we do not know how the spindle environment affects these dynamics. We developed methods for measuring two key parameters of microtubule plus-end dynamic instability in ...
Catecholaminergic connectivity to the inner ear, central auditory, and vocal motor circuitry in the plainfin midshipman fish porichthys notatus
Although the neuroanatomical distribution of catecholaminergic (CA) neurons has been well documented across all vertebrate classes, few studies have examined CA connectivity to physiologically and anatomically identified ...
pH dependent isotropic to nematic phase transitions in graphene oxide dispersions reveal droplet liquid crystalline phases
Size fractionation, amplified by the surface charge density of graphene oxide (GO) sheets, broadens the pH dependent isotropic (I) to nematic (N) phase transition in aqueous dispersions of graphene oxide (GO). In this ...
Presynaptic nanodomains : a tale of two synapses
(Frontiers Media, 2015-01-26)
Here we summarize the evidence from two “giant” presynaptic terminals—the squid giant synapse and the mammalian calyx of Held—supporting the involvement of nanodomain calcium signals in triggering of neurotransmitter ...
The savory swimmer swims north : a northern range extension of the blue crab Callinectes sapidus?
Worldwide, climate-change is shifting species distributions poleward. Here I present recent (2012-2014) observations of the blue crab, Callinectes sapidus, in the Gulf of Maine (GoM), north of its historical range of Cape ...
Ecological functions of uncultured microorganisms in the cobalt-rich ferromanganese crust of a seamount in the central Pacific are elucidated by fosmid sequencing
Cobalt-rich ferromanganese is an important seafloor mineral and is abundantly present in the seamount crusts. Such crusts form potential hotspots for biogeochemical activity and microbial diversity, yet our understanding ...
Species compositional differences on different-aged glacial landscapes drive contrasting responses of tundra to nutrient addition
In the northern foothills of the Brooks Range, Alaska, moist non-acidic tundra dominates more recently deglaciated upland landscapes, whereas moist acidic tundra dominates older upland landscapes. In previous studies, ...
Image analysis for biology