Now showing items 1-5 of 5

    • Chronic exposure to arsenic in the drinking water alters the expression of immune response genes in mouse lung 

      Kozul, Courtney D.; Hampton, Thomas H.; Davey, Jennifer C.; Gosse, Julie A.; Nomikos, Athena P.; Eisenhauer, Phillip L.; Weiss, Daniel J.; Thorpe, Jessica E.; Ihnat, Michael A.; Hamilton, Joshua W. (National Institute of Environmental Health Sciences, 2009-03-04)
      Chronic exposure to drinking water arsenic is a significant worldwide environmental health concern. Exposure to As is associated with an increased risk of lung disease, which may make it a unique toxicant, because lung ...
    • Cisplatin resistant spheroids model clinically relevant survival mechanisms in ovarian tumors 

      Chowanadisai, Winyoo; Messerli, Shanta M.; Miller, Daniel H.; Medina, Jamie E.; Hamilton, Joshua W.; Messerli, Mark A.; Brodsky, Alexander S. (Public Library of Science, 2016-03-17)
      The majority of ovarian tumors eventually recur in a drug resistant form. Using cisplatin sensitive and resistant cell lines assembled into 3D spheroids we profiled gene expression and identified candidate mechanisms and ...
    • Effects of low-dose drinking water arsenic on mouse fetal and postnatal growth and development 

      Kozul-Horvath, Courtney D.; Zandbergen, Fokko; Jackson, Brian P.; Enelow, Richard I.; Hamilton, Joshua W. (Public Library of Science, 2012-05-31)
      Arsenic (As) exposure is a significant worldwide environmental health concern. Chronic exposure via contaminated drinking water has been associated with an increased incidence of a number of diseases, including reproductive ...
    • Gene expression profile of peripheral blood lymphocytes from renal cell carcinoma patients treated with IL-2, Interferon-α and dendritic cell vaccine 

      Wolf, Benita; Schwarzer, Adrian; Cote, Anik L.; Hampton, Thomas H.; Schwaab, Thomas; Huarte, Eduardo; Tomlinson, Craig R.; Gui, Jiang; Fisher, Jan L.; Fadul, Camilo E.; Hamilton, Joshua W.; Ernstoff, Marc S. (Public Library of Science, 2012-12-03)
      Lymphocytes are a key component of the immune system and their differentiation and function are directly influenced by cancer. We examined peripheral blood lymphocyte (PBL) gene expression as a biomarker of illness and ...
    • Low-dose arsenic compromises the immune response to influenza A infection in vivo 

      Kozul, Courtney D.; Ely, Kenneth H.; Enelow, Richard I.; Hamilton, Joshua W. (National Institute of Environmental Health Sciences, 2009-05-20)
      Arsenic exposure is a significant worldwide environmental health concern. We recently reported that 5-week exposure to environmentally relevant levels (10 and 100 ppb) of As in drinking water significantly altered components ...