Now showing items 1-20 of 806

  • Accuracy and quality of massively parallel DNA pyrosequencing 

    Huse, Susan M.; Huber, Julie A.; Morrison, Hilary G.; Sogin, Mitchell L.; Mark Welch, David B. (BioMed Central, 2007-07-20)
    Massively parallel pyrosequencing systems have increased the efficiency of DNA sequencing, although the published per-base accuracy of a Roche GS20 is only 96%. In genome projects, highly redundant consensus assemblies can ...
  • Acidification increases microbial polysaccharide degradation in the ocean 

    Piontek, J.; Lunau, M.; Handel, N.; Borchard, C.; Wurst, M.; Engel, A. (Copernicus Publications on behalf of the European Geosciences Union, 2010-05-19)
    With the accumulation of anthropogenic carbon dioxide (CO2), a proceeding decline in seawater pH has been induced that is referred to as ocean acidification. The ocean's capacity for CO2 storage is strongly affected by ...
  • Acoustic detection and quantification of benthic egg beds of the squid Loligo opalescens in Monterey Bay, California 

    Foote, Kenneth G.; Hanlon, Roger T.; Iampietro, Pat J.; Kvitek, Rikk G. (Acoustical Society of America, 2006-02)
    The squid Loligo opalescens is a key species in the nearshore pelagic community of California, supporting the most valuable state marine fishery, yet the stock biomass is unknown. In southern Monterey Bay, extensive beds ...
  • Actin binding to WH2 domains regulates nuclear import of the multifunctional actin regulator JMY 

    Zuchero, J. Bradley; Belin, Brittany J.; Mullins, R. Dyche (American Society for Cell Biology, 2012-01-19)
    Junction-mediating and regulatory protein (JMY) is a regulator of both transcription and actin filament assembly. In response to DNA damage, JMY accumulates in the nucleus and promotes p53-dependent apoptosis. JMY's ...
  • Acute increase of α-synuclein inhibits synaptic vesicle recycling evoked during intense stimulation 

    Busch, David J.; Oliphint, Paul A.; Walsh, Rylie B.; Banks, Susan M. L.; Woods, Wendy S.; George, Julia M.; Morgan, Jennifer R. (American Society for Cell Biology, 2014-10-01)
    Parkinson's disease is associated with multiplication of the α-synuclein gene and abnormal accumulation of the protein. In animal models, α-synuclein overexpression broadly impairs synaptic vesicle trafficking. However, ...
  • Adaptable night camouflage by cuttlefish 

    Hanlon, Roger T.; Naud, Marie-Jose; Forsythe, John W.; Hall, Karina; Watson, Anya C.; McKechnie, Joy (University of Chicago Press, 2007-02-12)
    Cephalopods are well known for their diverse, quick‐changing camouflage in a wide range of shallow habitats worldwide. However, there is no documentation that cephalopods use their diverse camouflage repertoire at night. ...
  • Adaptive evolution of voltage-gated sodium channels : the first 800 million years 

    Zakon, Harold H. (2012-04)
    Voltage-gated Na+-permeable (Nav) channels form the basis for electrical excitability in animals. Nav channels evolved from Ca2+ channels and were present in the common ancestor of choanoflagellates and animals although ...
  • Adjustment of forest ecosystem root respiration as temperature warms 

    Burton, Andrew J.; Melillo, Jerry M.; Frey, Serita D. (2008-06)
    Adjustment of ecosystem root respiration to warmer climatic conditions can alter the autotrophic portion of soil respiration and influence the amount of carbon available for biomass production. We examined 44 published ...
  • Aggregate measures of ecosystem services : can we take the pulse of nature? 

    Meyerson, Laura A.; Baron, Jill; Melillo, Jerry M.; Naiman, Robert J.; O'Malley, Robin I.; Orians, Gordon; Palmer, Margaret A.; Pfaff, Alexander S. P.; Running, Steven W.; Sala, Osvaldo E. (Ecological Society of America, 2005-02)
    National scale aggregate indicators of ecosystem services are useful for stimulating and supporting a broad public discussion about trends in the provision of these services. There are important considerations involved in ...
  • An algorithm to estimate unsteady and quasi-steady pressure fields from velocity field measurements 

    Dabiri, John O.; Bose, Sanjeeb; Gemmell, Brad J.; Colin, Sean P.; Costello, John H. (Company of Biologists, 2013-10-10)
    We describe and characterize a method for estimating the pressure field corresponding to velocity field measurements such as those obtained by using particle image velocimetry. The pressure gradient is estimated from a ...
  • Alkenone producers inferred from well-preserved 18S rDNA in Greenland lake sediments 

    D'Andrea, William J.; Lage, Melissa; Martiny, Jennifer B. H.; Laatsch, Abby D.; Amaral-Zettler, Linda A.; Sogin, Mitchell L.; Huang, Yongsong (American Geophysical Union, 2006-09-19)
    The 18S ribosomal DNA (rDNA) sequences of haptophyte algae were successfully amplified using the polymerase chain reaction (PCR) from water filtrate, surface sediments, and a late-Holocene sediment sample (∼1000 years old) ...
  • All-optical mapping of barrel cortex circuits based on simultaneous voltage-sensitive dye imaging and channelrhodopsin-mediated photostimulation 

    Lo, Shun Qiang; Koh, Dawn X. P.; Sng, Judy C. G.; Augustine, George J. (SPIE, 2015-03-31)
    We describe an experimental approach that uses light to both control and detect neuronal activity in mouse barrel cortex slices: blue light patterned by a digital micromirror array system allowed us to photostimulate ...
  • Amazon deforestation alters small stream structure, nitrogen biogeochemistry and connectivity to larger rivers 

    Deegan, Linda A.; Neill, Christopher; Haupert, Christie L.; Ballester, M. Victoria R.; Krusche, Alex V.; Victoria, Reynaldo L.; Thomas, Suzanne M.; de Moor, Emily (2010-08-29)
    Human activities that modify land cover can alter the structure and biogeochemistry of small streams but these effects are poorly known over large regions of the humid tropics where rates of forest clearing are high. We ...
  • The Amazon frontier of land-use change : croplands and consequences for greenhouse gas emissions 

    Galford, Gillian L.; Melillo, Jerry M.; Mustard, John F.; Cerri, Carlos E. P.; Cerri, Carlos C. (American Meteorological Society, 2010-10-28)
    The Brazilian Amazon is one of the most rapidly developing agricultural frontiers in the world. The authors assess changes in cropland area and the intensification of cropping in the Brazilian agricultural frontier state ...
  • Ambiguities in the relationship between gonadal steroids and reproduction in axolotls (Ambystoma mexicanum) 

    Eisthen, Heather L.; Krause, Brianne Chung (2011-11-01)
    Axolotls (Ambystoma mexicanum) are aquatic salamanders that are widely used in research. Axolotls have been bred in laboratories for nearly 150 years, yet little is known about the basic biology of reproduction in these ...
  • The amino terminus of tau inhibits kinesin-dependent axonal transport: Implications for filament toxicity 

    LaPointe, Nichole E.; Morfini, Gerardo A.; Pigino, Gustavo F.; Gaisina, Irina N.; Kozikowski, Alan P.; Binder, Lester I.; Brady, Scott T. (2008-04)
    The neuropathology of Alzheimer’s disease (AD) and other tauopathies is characterized by filamentous deposits of the microtubule-associated protein tau, but the relationship between tau polymerization and neurotoxicity ...
  • Aminoglycoside-induced damage in the statocyst of the longfin inshore squid, Doryteuthis pealeii 

    Scharr, Alexandra L.; Mooney, T. Aran; Schweizer, Felix E.; Ketten, Darlene R. (Marine Biological Laboratory, 2014-08-01)
    Squid are a significant component of the marine biomass and are a long-established model organism in experimental neurophysiology. The squid statocyst senses linear and angular acceleration and is the best candidate for ...
  • Analysis of expressed sequence tags of the cyclically parthenogenetic rotifer Brachionus plicatilis 

    Suga, Koushirou; Mark Welch, David B.; Tanaka, Yukari; Sakakura, Yoshitaka; Hagiwara, Atsushi (Public Library of Science, 2007-08-01)
    Rotifers are among the most common non-arthropod animals and are the most experimentally tractable members of the basal assemblage of metazoan phyla known as Gnathifera. The monogonont rotifer Brachionus plicatilis is a ...
  • An analysis of the carbon balance of the Arctic Basin from 1997 to 2006 

    McGuire, A. David; Hayes, Daniel J.; Kicklighter, David W.; Manizza, Manfredi; Zhuang, Qianlai; Chen, Min; Follows, Michael J.; Gurney, Kevin R.; McClelland, James W.; Melillo, Jerry M.; Peterson, Bruce J.; Prinn, Ronald G. (2010-06-18)
    This study used several model-based tools to analyze the dynamics of the Arctic Basin between 1997 and 2006 as a linked system of land-ocean-atmosphere C exchange. The analysis estimates that terrestrial areas of the ...
  • Analysis, optimization and verification of Illumina-generated 16S rRNA gene amplicon surveys 

    Nelson, Michael C.; Morrison, Hilary G.; Benjamino, Jacquelynn; Grim, Sharon L.; Graf, Joerg (Public Library of Science, 2014-04-10)
    The exploration of microbial communities by sequencing 16S rRNA genes has expanded with low-cost, high-throughput sequencing instruments. Illumina-based 16S rRNA gene sequencing has recently gained popularity over 454 ...