Now showing items 296-315 of 874

    • The freshwater system west of the Antarctic Peninsula : spatial and temporal changes 

      Meredith, Michael P.; Venables, Hugh J.; Clarke, Andrew; Ducklow, Hugh W.; Erickson, Matthew; Leng, Melanie J.; Lenaerts, Jan T. M.; van den Broeke, Michiel R. (American Meteorological Society, 2013-03-01)
      Climate change west of the Antarctic Peninsula is the most rapid of anywhere in the Southern Hemisphere, with associated changes in the rates and distributions of freshwater inputs to the ocean. Here, results from the first ...
    • Functional consequences of the asymmetric architecture of the ctenophore statocyst 

      Tamm, Sidney L. (Marine Biological Laboratory, 2015-10-01)
      Ctenophores, or comb jellies, are geotactic with a statocyst that controls the activity of the eight ciliary comb rows. If a ctenophore is tilted or displaced from a position of vertical balance, it rights itself by ...
    • Functional organization of hsp70 cluster in camel (Camelus dromedarius) and other mammals 

      Garbuz, David G.; Astakhova, Lubov N.; Zatsepina, Olga G.; Arkhipova, Irina R.; Nudler, Eugene; Evgenev, Michael B. (Public Library of Science, 2011-11-09)
      Heat shock protein 70 (Hsp70) is a molecular chaperone providing tolerance to heat and other challenges at the cellular and organismal levels. We sequenced a genomic cluster containing three hsp70 family genes linked with ...
    • Functional overlap of microtubule assembly factors in chromatin-promoted spindle assembly 

      Groen, Aaron C.; Maresca, Thomas J.; Gatlin, Jesse C.; Salmon, Edward D.; Mitchison, Timothy J. (American Society for Cell Biology, 2009-04-15)
      Distinct pathways from centrosomes and chromatin are thought to contribute in parallel to microtubule nucleation and stabilization during animal cell mitotic spindle assembly, but their full mechanisms are not known. We ...
    • Functional significance of the taper of vertebrate cone photoreceptors 

      Harosi, Ferenc I.; Flamarique, Inigo Novales (Rockefeller University Press, 2012-01-16)
      Vertebrate photoreceptors are commonly distinguished based on the shape of their outer segments: those of cones taper, whereas the ones from rods do not. The functional advantages of cone taper, a common occurrence in ...
    • Functional states of kinetochores revealed by laser microsurgery and fluorescent speckle microscopy 

      LaFountain, James R.; Cohan, Christopher S.; Oldenbourg, Rudolf (American Society of Cell Biology, 2011-10-26)
      The impact of mechanical forces on kinetochore motility was investigated using laser microsurgery to detach kinetochores with associated chromatin (K fragment) from meiotic chromosomes in spermatocytes from the crane fly ...
    • Functional structure of the mitral cell dendritic tuft in the rat olfactory bulb 

      Djurisic, Maja; Popovic, Marko; Carnevale, Nicholas; Zecevic, Dejan (Society for Neuroscience, 2008-04-09)
      The input–output transform performed by mitral cells, the principal projection neurons of the olfactory bulb, is one of the key factors in understanding olfaction. We used combined calcium and voltage imaging from the same ...
    • A functional update of the Escherichia coli K-12 genome 

      Serres, Margrethe H.; Gopal, Shuba; Nahum, Laila A.; Liang, Ping; Gaasterland, Terry; Riley, Monica (BioMed Central, 2001-08-20)
      Background: Since the genome of Escherichia coli K-12 was initially annotated in 1997, additional functional information based on biological characterization and functions of sequence-similar proteins has become available. ...
    • Future effects of ozone on carbon sequestration and climate change policy using a global biogeochemical model 

      Felzer, Benjamin S.; Reilly, John M.; Melillo, Jerry M.; Kicklighter, David W.; Sarofim, Marcus C.; Wang, C.; Prinn, Ronald G.; Zhuang, Qianlai (2004-10-29)
      Exposure of plants to ozone inhibits photosynthesis and therefore reduces vegetation production and carbon sequestration. The reduced carbon storage would then require further reductions in fossil fuel emissions to meet ...
    • GenBank and PubMed : how connected are they? 

      Miller, Holly; Norton, Cathy N.; Sarkar, Indra Neil (BioMed Central, 2009-06-09)
      GenBank(R) is a public repository of all publicly available molecular sequence data from a range of sources. In addition to relevant metadata (e.g., sequence description, source organism and taxonomy), publication information ...
    • Gene duplications and evolution of vertebrate voltage-gated sodium channels 

      Novak, Alicia E.; Jost, Manda C.; Lu, Ying; Taylor, Alison D.; Zakon, Harold H.; Ribera, Angeles B. (2006-03-01)
      Voltage-gated sodium channels underlie action potential generation in excitable tissue. To establish the evolutionary mechanisms that shaped the vertebrate sodium channel a-subunit (SCNA) gene family and their encoded ...
    • Gene expression level influences amino acid usage, but not codon usage, in the tsetse fly endosymbiont Wigglesworthia 

      Herbeck, Joshua T.; Wall, Dennis P.; Wernegreen, Jennifer J. (Society for General Mircobiology, 2003)
      Wigglesworthia glossinidia brevipalpis, the obligate bacterial endosymbiont of the tsetse fly Glossina brevipalpis, is characterized by extreme genome reduction and AT nucleotide composition bias. Here, multivariate ...
    • Gene expression profile of peripheral blood lymphocytes from renal cell carcinoma patients treated with IL-2, Interferon-α and dendritic cell vaccine 

      Wolf, Benita; Schwarzer, Adrian; Cote, Anik L.; Hampton, Thomas H.; Schwaab, Thomas; Huarte, Eduardo; Tomlinson, Craig R.; Gui, Jiang; Fisher, Jan L.; Fadul, Camilo E.; Hamilton, Joshua W.; Ernstoff, Marc S. (Public Library of Science, 2012-12-03)
      Lymphocytes are a key component of the immune system and their differentiation and function are directly influenced by cancer. We examined peripheral blood lymphocyte (PBL) gene expression as a biomarker of illness and ...
    • Gene fusions and gene duplications : relevance to genomic annotation and functional analysis 

      Serres, Margrethe H.; Riley, Monica (BioMed Central, 2005-03-09)
      Background: Escherichia coli a model organism provides information for annotation of other genomes. Our analysis of its genome has shown that proteins encoded by fused genes need special attention. Such composite ...
    • Genetic identity determines risk of post-settlement mortality of a marine fish 

      Vigliola, Laurent; Doherty, Peter J.; Meekan, Mark G.; Drown, Devin M.; Jones, M. Elizabeth; Barber, Paul H. (Ecological Society of America, 2007-05)
      Longitudinal sampling of four cohorts of Neopomacentrus filamentosus, a common tropical damselfish from Dampier Archipelago, Western Australia, revealed the evolution of size structure after settlement. Light traps collected ...
    • Genome reconstructions indicate the partitioning of ecological functions inside a phytoplankton bloom in the Amundsen Sea, Antarctica 

      Delmont, Tom O.; Eren, A. Murat; Vineis, Joseph H.; Post, Anton F. (Frontiers Media, 2015-10-26)
      Antarctica polynyas support intense phytoplankton blooms, impacting their environment by a substantial depletion of inorganic carbon and nutrients. These blooms are dominated by the colony-forming haptophyte Phaeocystis ...
    • Genome structure of bdelloid rotifers : shaped by asexuality or desiccation? 

      Gladyshev, Eugene A.; Arkhipova, Irina R. (2010-01)
      Bdelloid rotifers are microscopic invertebrate animals best known for their ancient asexuality and the ability to survive desiccation at any life stage. Both factors are expected to have a profound influence on their ...
    • Genomic analysis of carbon source metabolism of Shewanella oneidensis MR-1 : predictions versus experiments 

      Serres, Margrethe H.; Riley, Monica (American Society for Microbiology, 2006-07)
      Genomic sequences have been used to find the genetic foundation for carbon source metabolism in Shewanella oneidensis MR-1. Annotated S. oneidensis MR-1 gene products were examined for their sequence similarity to enzymes ...
    • Genomic and metabolic diversity of Marine Group I Thaumarchaeota in the mesopelagic of two subtropical gyres 

      Swan, Brandon K.; Chaffin, Mark D.; Martinez-Garcia, Manuel; Morrison, Hilary G.; Field, Erin K.; Poulton, Nicole J.; Masland, E. Dashiell P.; Harris, Christopher C.; Sczyrba, Alexander; Chain, Patrick S. G.; Koren, Sergey; Woyke, Tanja; Stepanauskas, Ramunas (Public Library of Science, 2014-04-17)
      Marine Group I (MGI) Thaumarchaeota are one of the most abundant and cosmopolitan chemoautotrophs within the global dark ocean. To date, no representatives of this archaeal group retrieved from the dark ocean have been ...
    • Genomic evidence for ameiotic evolution in the bdelloid rotifer Adineta vaga 

      Flot, Jean-Francois; Hespeels, Boris; Li, Xiang; Noel, Benjamin; Arkhipova, Irina R.; Danchin, Etienne G. J.; Hejno, Andreas; Henrissat, Bernard; Koszul, Romain; Aury, Jean-Marc; Barbe, Valerie; Barthelemy, Roxane-Marie; Bast, Jens; Bazykin, Georgii A.; Chabrol, Olivier; Couloux, Arnaud; Da Rocha, Martine; Da Silva, Corinne; Gladyshev, Eugene A.; Gouret, Philippe; Hallatschek, Oskar; Hecox-Lea, Bette; Labadie, Karine; Lejeune, Benjamin; Piskurek, Oliver; Poulain, Julie; Rodriguez, Fernando; Ryan, Joseph F.; Vakhrusheva, Olga A.; Wajnberg, Eric; Wirth, Benedicte; Yushenova, Irina A.; Kellis, Manolis; Kondrashov, Alexey S.; Mark Welch, David B.; Pontarotti, Pierre; Weissenbach, Jean; Wincker, Patrick; Jaillon, Olivier; Van Doninck, Karine (Nature Publishing Group, 2013-07-21)
      Loss of sexual reproduction is considered an evolutionary dead end for metazoans, but bdelloid rotifers challenge this view as they appear to have persisted asexually for millions of years1. Neither male sex organs nor ...