Lack of growth enhancement by exogenous growth hormone treatment in yellow perch (Perca flavescens) in four separate experiments
Malison, Jeffrey A.
Barry, Terence P.
Held, James A.
Roberts, Steven B.
Goetz, Frederick W.
MetadataShow full item record
The effect of exogenous growth hormone (GH) treatment on the growth of juvenile yellow perch (Perca flavescens) was investigated in four experiments. In the first two experiments, juvenile yellow perch were reared at either 13°C or 21°C, and injected weekly with bovine GH (bGH) at 0.1, 1.0 or 10.0 μg/g body weight for 84 days. No significant growth enhancement in GH-treated fish was measured in fish in either of the experiments. In the third experiment, juvenile yellow perch were treated with estradiol-17β (E2, 15 μg/g of diet), bGH (1.0 μg/g body weight) injected weekly or both hormones for 70 days at 21°C. E2 alone stimulated growth, but no further growth stimulation occurred in the E2 + bGH-treated fish. In addition, no growth enhancement was found in fish treated with bGH alone. We measured no difference in serum insulin-like growth factor-I (IGF-I) levels between the treatment groups at 12 and 24 h after the final injection of GH; however, a drop in IGF-I levels after 24 h was observed. In a fourth study, the effect of recombinant yellow perch GH (rypGH, 0.2 or 1.0 μg/g body weight) injected weekly was evaluated in yellow perch juveniles. The fish were reared for 42 days at 18°C. Neither GH dosages improved growth compared to control-injected and non-injected fish. Taken together, the lack of effect of mammalian GH or rypGH in our experiments suggests (1) low binding affinity between these hormones and the GH receptor in yellow perch, (2) that the endogenous GH levels were already at biologically maximal levels or (3) that other endocrine factors are needed in order for GH to promote yellow perch growth. The reduction in IGF-I levels 24 h after handling suggests a negative effect of handling stress on the GH-IGF-I axis in yellow perch.
Author Posting. © The Authors, 2005. This is the author's version of the work. It is posted here by permission of Elsevier B. V. for personal use, not for redistribution. The definitive version was published in Aquaculture 250 (2005): 471-479, doi:10.1016/j.aquaculture.2005.03.019.
Showing items related by title, author, creator and subject.
Coherent patterns in bacterial growth, growth efficiency, and leucine metabolism along a northeastern Pacific inshore-offshore transect del Giorgio, Paul A.; Condon, Robert H.; Bouvier, Thierry; Longnecker, Krista; Bouvier, Corinne; Sherr, Evelyn; Gasol, Josep M. (Association for the Sciences of Limnology and Oceanography, 2011-01)We investigated the patterns in bacterial growth, production, respiration, growth efficiency (BGE), and bacterial leucine respiration and C-to-leucine yield (i.e., conversion factor [CF]) along a transect off the coast of ...
Validated age and growth estimates for Carcharhinus obscurus in the northwestern Atlantic Ocean, with pre- and post management growth comparisons Natanson, Lisa J.; Gervelis, Brian J.; Winton, Megan V.; Hamady, Li Ling; Gulak, Simon J. B.; Carlson, John K. (Springer, 2013-11-19)Age and growth estimates for the dusky shark, Carcharhinus obscurus, were derived from vertebral centra collected in the northwestern Atlantic Ocean. Sample collection spanned the years prior to and following the implementation ...
Patrut, Adrian; Mayne, Diana H.; von Reden, Karl F.; Lowy, Daniel A.; Venter, Sarah; McNichol, Ann P.; Roberts, Mark L.; Margineanu, Dragos (Dept. of Geosciences, University of Arizona, 2010-08)In 2008, a large African baobab (Adansonia digitata L.) from Makulu Makete, South Africa, split vertically into 2 sections, revealing a large enclosed cavity. Several wood samples collected from the cavity were processed ...