Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita
Danchin, Etienne G. J.
Blok, Vivian C.
Coutinho, Pedro M.
Da Silva, Corinne
De Luca, Francesca
Goldstone, Jared V.
Maier, Tom R.
Markov, Gabriel V.
van Ghelder, Cyril
Baum, Thomas J.
Davis, Eric L
Ewbank, Jonathan J.
Jones, John T.
Maule, Aaron G.
MetadataShow full item record
Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall–degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.
© 2008 Nature Publishing Group. This article is distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike license. The definitive version was published in Nature Biotechnology 26 (2008): 909-915, doi:10.1038/nbt.1482.
The following license files are associated with this item:
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-sa/3.0/
Showing items related by title, author, creator and subject.
Mottl, Michael J.; Seewald, Jeffrey S.; Wheat, C. Geoffrey; Tivey, Margaret K.; Michael, Peter J.; Proskurowski, Giora; McCollom, Thomas M.; Reeves, Eoghan P.; Sharkey, Jessica; You, Chen-Feng; Chan, Lui-Heung; Pichler, Thomas (2010-12-08)The Eastern Lau Spreading Center (ELSC) is the southernmost part of the back-arc spreading axis in the Lau Basin, west of the Tonga trench and the active Tofua volcanic arc. Over its 397-km length it exhibits large and ...
Shcherbina, Andrey Y.; Sundermeyer, Miles A.; Kunze, Eric; D’Asaro, Eric; Badin, Gualtiero; Birch, Daniel; Brunner-Suzuki, Anne-Marie E. G.; Callies, Joern; Cervantes, Brandy T. Kuebel; Claret, Mariona; Concannon, Brian; Early, Jeffrey; Ferrari, Raffaele; Goodman, Louis; Harcourt, Ramsey R.; Klymak, Jody M.; Lee, Craig M.; Lelong, M.-Pascale; Levine, Murray D.; Lien, Ren-Chieh; Mahadevan, Amala; McWilliams, James C.; Molemaker, M. Jeroen; Mukherjee, Sonaljit; Nash, Jonathan D.; Ozgokmen, Tamay M.; Pierce, Stephen D.; Ramachandran, Sanjiv; Samelson, Roger M.; Sanford, Thomas B.; Shearman, R. Kipp; Skyllingstad, Eric D.; Smith, K. Shafer; Tandon, Amit; Taylor, John R.; Terray, Eugene A.; Thomas, Leif N.; Ledwell, James R. (American Meteorological Society, 2015-08)Lateral stirring is a basic oceanographic phenomenon affecting the distribution of physical, chemical, and biological fields. Eddy stirring at scales on the order of 100 km (the mesoscale) is fairly well understood and ...
Controls on dissolved cobalt in surface waters of the Sargasso Sea : comparisons with iron and aluminum Shelley, R. U.; Sedwick, Peter N.; Bibby, Thomas S.; Cabedo-Sanz, P.; Church, Thomas M.; Johnson, Rodney J.; Macey, A. I.; Marsay, Christopher M.; Sholkovitz, Edward R.; Ussher, Simon J.; Worsfold, Paul J.; Lohan, M. C. (American Geophysical Union, 2012-05-19)Dissolved cobalt (dCo), iron (dFe) and aluminum (dAl) were determined in water column samples along a meridional transect (~31°N to 24°N) south of Bermuda in June 2008. A general north-to-south increase in surface ...