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dc.contributor.authorBurnett, Karen G.
dc.contributor.authorBain, Lisa J.
dc.contributor.authorBaldwin, William S.
dc.contributor.authorCallard, Gloria V.
dc.contributor.authorCohen, Sarah
dc.contributor.authorDi Giulio, Richard T.
dc.contributor.authorEvans, David H.
dc.contributor.authorGomez-Chiarri, Marta
dc.contributor.authorHahn, Mark E.
dc.contributor.authorHoover, Cindi A.
dc.contributor.authorKarchner, Sibel I.
dc.contributor.authorKatoh, Fumi
dc.contributor.authorMacLatchy, Deborah L.
dc.contributor.authorMarshall, William S.
dc.contributor.authorMeyer, Joel N.
dc.contributor.authorNacci, Diane E.
dc.contributor.authorOleksiak, Marjorie F.
dc.contributor.authorRees, Bernard B.
dc.contributor.authorSinger, Thomas D.
dc.contributor.authorStegeman, John J.
dc.contributor.authorTowle, David W.
dc.contributor.authorVan Veld, Peter A.
dc.contributor.authorVogelbein, Wolfgang K.
dc.contributor.authorWhitehead, Andrew
dc.contributor.authorWinn, Richard N.
dc.contributor.authorCrawford, Douglas L.
dc.date.accessioned2008-01-22T19:38:26Z
dc.date.available2008-01-22T19:38:26Z
dc.date.issued2007-09-01
dc.identifier.urihttp://hdl.handle.net/1912/2033
dc.descriptionAuthor Posting. © Elsevier B.V., 2007. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Comparative Biochemistry and Physiology Part D: Genomics and Proteomics 2 (2007): 257-286, doi:10.1016/j.cbd.2007.09.001.en
dc.description.abstractA strong foundation of basic and applied research documents that the estuarine fish Fundulus heteroclitus and related species are unique laboratory and field models for understanding how individuals and populations interact with their environment. In this paper we summarize an extensive body of work examining the adaptive responses of Fundulus species to environmental conditions, and describe how this research has contributed importantly to our understanding of physiology, gene regulation, toxicology, and ecological and evolutionary genetics of teleosts and other vertebrates. These explorations have reached a critical juncture at which advancement is hindered by the lack of genomic resources for these species. We suggest that a more complete genomics toolbox for F. heteroclitus and related species will permit researchers to exploit the power of this model organism to rapidly advance our understanding of fundamental biological and pathological mechanisms among vertebrates, as well as ecological strategies and evolutionary processes common to all living organisms.en
dc.description.sponsorshipThis material is based on work supported by grants from the National Science Foundation DBI-0420504 (LJB), OCE 0308777 (DLC, RNW, BBR), BES-0553523 (AW), IBN 0236494 (BBR), IOB-0519579 (DHE), IOB-0543860 (DWT), FSML-0533189 (SC); National Institute of Health NIEHS P42-ES007381(GVC, MEH), P42-ES10356 (RTD), ES011588 (MFO); and NCRR P20 RR-016463 (DWT); Natural Sciences and Engineering Research Council of Canada Discovery (DLM, TDS, WSM) and Collaborative Research and Development Programs (DLM); NOAA/National Sea Grant NA86RG0052 (LJB), NA16RG2273 (SIK, MEH,GVC, JJS); Environmental Protection Agency U91620701 (WSB), R82902201(SC) and EPA’s Office of Research and Development (DEN).en
dc.format.mimetypeapplication/pdf
dc.language.isoen_USen
dc.relation.urihttps://doi.org/10.1016/j.cbd.2007.09.001
dc.subjectFundulus heteroclitusen
dc.subjectPhysiological genomicsen
dc.subjectEcological genomicsen
dc.subjectEvolutionary genomicsen
dc.subjectToxicogenomicsen
dc.subjectEnvironmental genomicsen
dc.titleFundulus as the premier teleost model in environmental biology : opportunities for new insights using genomicsen
dc.typePreprinten


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