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    Fundulus as the premier teleost model in environmental biology : opportunities for new insights using genomics

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    Fundulus white paper revised final.pdf (374.7Kb)
    Date
    2007-09-01
    Author
    Burnett, Karen G.  Concept link
    Bain, Lisa J.  Concept link
    Baldwin, William S.  Concept link
    Callard, Gloria V.  Concept link
    Cohen, Sarah  Concept link
    Di Giulio, Richard T.  Concept link
    Evans, David H.  Concept link
    Gomez-Chiarri, Marta  Concept link
    Hahn, Mark E.  Concept link
    Hoover, Cindi A.  Concept link
    Karchner, Sibel I.  Concept link
    Katoh, Fumi  Concept link
    MacLatchy, Deborah L.  Concept link
    Marshall, William S.  Concept link
    Meyer, Joel N.  Concept link
    Nacci, Diane E.  Concept link
    Oleksiak, Marjorie F.  Concept link
    Rees, Bernard B.  Concept link
    Singer, Thomas D.  Concept link
    Stegeman, John J.  Concept link
    Towle, David W.  Concept link
    Van Veld, Peter A.  Concept link
    Vogelbein, Wolfgang K.  Concept link
    Whitehead, Andrew  Concept link
    Winn, Richard N.  Concept link
    Crawford, Douglas L.  Concept link
    Metadata
    Show full item record
    Citable URI
    https://hdl.handle.net/1912/2033
    As published
    https://doi.org/10.1016/j.cbd.2007.09.001
    Keyword
     Fundulus heteroclitus; Physiological genomics; Ecological genomics; Evolutionary genomics; Toxicogenomics; Environmental genomics 
    Abstract
    A strong foundation of basic and applied research documents that the estuarine fish Fundulus heteroclitus and related species are unique laboratory and field models for understanding how individuals and populations interact with their environment. In this paper we summarize an extensive body of work examining the adaptive responses of Fundulus species to environmental conditions, and describe how this research has contributed importantly to our understanding of physiology, gene regulation, toxicology, and ecological and evolutionary genetics of teleosts and other vertebrates. These explorations have reached a critical juncture at which advancement is hindered by the lack of genomic resources for these species. We suggest that a more complete genomics toolbox for F. heteroclitus and related species will permit researchers to exploit the power of this model organism to rapidly advance our understanding of fundamental biological and pathological mechanisms among vertebrates, as well as ecological strategies and evolutionary processes common to all living organisms.
    Description
    Author Posting. © Elsevier B.V., 2007. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Comparative Biochemistry and Physiology Part D: Genomics and Proteomics 2 (2007): 257-286, doi:10.1016/j.cbd.2007.09.001.
    Collections
    • Biology
    Suggested Citation
    Preprint: Burnett, Karen G., Bain, Lisa J., Baldwin, William S., Callard, Gloria V., Cohen, Sarah, Di Giulio, Richard T., Evans, David H., Gomez-Chiarri, Marta, Hahn, Mark E., Hoover, Cindi A., Karchner, Sibel I., Katoh, Fumi, MacLatchy, Deborah L., Marshall, William S., Meyer, Joel N., Nacci, Diane E., Oleksiak, Marjorie F., Rees, Bernard B., Singer, Thomas D., Stegeman, John J., Towle, David W., Van Veld, Peter A., Vogelbein, Wolfgang K., Whitehead, Andrew, Winn, Richard N., Crawford, Douglas L., "Fundulus as the premier teleost model in environmental biology : opportunities for new insights using genomics", 2007-09-01, https://doi.org/10.1016/j.cbd.2007.09.001, https://hdl.handle.net/1912/2033
     

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