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dc.contributor.authorGladyshev, Eugene A.  Concept link
dc.contributor.authorMeselson, Matthew  Concept link
dc.contributor.authorArkhipova, Irina R.  Concept link
dc.date.accessioned2007-04-27T14:47:17Z
dc.date.available2007-04-27T14:47:17Z
dc.date.issued2006-09-12
dc.identifier.urihttps://hdl.handle.net/1912/1585
dc.descriptionAuthor Posting. © The Author(s), 2006. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Gene 390 (2007): 136-145, doi:10.1016/j.gene.2006.09.025.en
dc.description.abstractRotifers of class Bdelloidea, a group of aquatic invertebrates in which males and meiosis have never been documented, are also unusual in their lack of multicopy LINE-like and gypsy-like retrotransposons, groups inhabiting the genomes of nearly all other metazoans. Bdelloids do contain numerous DNA transposons, both intact and decayed, and domesticated Penelope-like retroelements Athena, concentrated at telomeric regions. Here we describe two LTR retrotransposons, each found at low copy number in a different bdelloid species, which define a clade different from previously known clades of LTR retrotransposons. Like bdelloid DNA transposons and Athena, these elements have been found preferentially in telomeric regions. Unlike bdelloid DNA transposons, many of which are decayed, the newly described elements, named Vesta and Juno, inhabiting the genomes of Philodina roseola and Adineta vaga, respectively, appear to be intact and to represent recent insertions, possibly from an exogenous source. We describe the retrovirus-like structure of the new elements, containing gag, pol, and env-like open reading frames, and discuss their possible origins, transmission, and behavior in bdelloid genomes.en
dc.description.sponsorshipWe thank the US National Science Foundation (MCB-0614142) and the National Institutes of Health (5R01GM072708-02) for financial support.en
dc.format.mimetypeapplication/pdf
dc.language.isoen_USen
dc.relation.urihttps://doi.org/10.1016/j.gene.2006.09.025
dc.subjectLTR retrotransposonsen
dc.subjectAsexual reproductionen
dc.subjectReverse transcriptaseen
dc.subjectIntegraseen
dc.subjectGagen
dc.subjectPolen
dc.subjectEnven
dc.titleA deep-branching clade of retrovirus-like retrotransposons in bdelloid rotifersen
dc.typePreprinten


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