A deep-branching clade of retrovirus-like retrotransposons in bdelloid rotifers

View/ Open
Date
2006-09-12Author
Gladyshev, Eugene A.
Concept link
Meselson, Matthew
Concept link
Arkhipova, Irina R.
Concept link
Metadata
Show full item recordCitable URI
https://hdl.handle.net/1912/1585As published
https://doi.org/10.1016/j.gene.2006.09.025Keyword
LTR retrotransposons; Asexual reproduction; Reverse transcriptase; Integrase; Gag; Pol; EnvAbstract
Rotifers of class Bdelloidea, a group of aquatic invertebrates in which males and meiosis
have never been documented, are also unusual in their lack of multicopy LINE-like and
gypsy-like retrotransposons, groups inhabiting the genomes of nearly all other
metazoans. Bdelloids do contain numerous DNA transposons, both intact and decayed,
and domesticated Penelope-like retroelements Athena, concentrated at telomeric
regions. Here we describe two LTR retrotransposons, each found at low copy number in
a different bdelloid species, which define a clade different from previously known clades
of LTR retrotransposons. Like bdelloid DNA transposons and Athena, these elements
have been found preferentially in telomeric regions. Unlike bdelloid DNA transposons,
many of which are decayed, the newly described elements, named Vesta and Juno,
inhabiting the genomes of Philodina roseola and Adineta vaga, respectively, appear to
be intact and to represent recent insertions, possibly from an exogenous source. We
describe the retrovirus-like structure of the new elements, containing gag, pol, and env-like
open reading frames, and discuss their possible origins, transmission, and behavior
in bdelloid genomes.
Description
Author Posting. © The Author(s), 2006. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Gene 390 (2007): 136-145, doi:10.1016/j.gene.2006.09.025.
Suggested Citation
Preprint: Gladyshev, Eugene A., Meselson, Matthew, Arkhipova, Irina R., "A deep-branching clade of retrovirus-like retrotransposons in bdelloid rotifers", 2006-09-12, https://doi.org/10.1016/j.gene.2006.09.025, https://hdl.handle.net/1912/1585Related items
Showing items related by title, author, creator and subject.
-
Rotifer rDNA-specific R9 retrotransposable elements generate an exceptionally long target site duplication upon insertion
Gladyshev, Eugene A.; Arkhipova, Irina R. (2009-08)Ribosomal DNA genes in many eukaryotes contain insertions of non-LTR retrotransposable elements belonging to the R2 clade. These elements persist in the host genomes by inserting site-specifically into multicopy target ... -
Endonuclease-containing Penelope retrotransposons in the bdelloid rotifer Adineta vaga exhibit unusual structural features and play a role in expansion of host gene families
Arkhipova, Irina R.; Yushenova, Irina A.; Rodriguez, Fernando (BioMed Central, 2013-08-27)Penelope-like elements (PLEs) are an enigmatic group of retroelements sharing a common ancestor with telomerase reverse transcriptases. In our previous studies, we identified endonuclease-deficient PLEs that are associated ... -
Distribution and phylogeny of Penelope-like elements in eukaryotes
Arkhipova, Irina R. (Oxford University Press, 2006-10)Penelope-like elements (PLEs) are a relatively little studied class of eukaryotic retroelements, distinguished by the presence of the GIY-YIG endonuclease domain, the ability of some representatives to retain introns, and ...