EGenBio : a data management system for evolutionary genomics and biodiversity
Citable URI
http://hdl.handle.net/1912/1279As published
http://dx.doi.org/10.1186/1471-2105-7-S2-S7DOI
10.1186/1471-2105-7-S2-S7Abstract
EGenBio is a system for manipulation and filtering of large numbers of sequences,
integrating curated sequence alignments and phylogenetic trees, managing evolutionary analyses, and visualizing their output. EGenBio is organized into three conceptual divisions, Evolution, Genomics, and Biodiversity. The Genomics division includes tools for selecting pre-aligned sequences
from different genes and species, and for modifying and filtering these alignments for further
analysis. Species searches are handled through queries that can be modified based on a tree-based navigation system and saved. The Biodiversity division contains tools for analyzing individual sequences or sequence alignments, whereas the Evolution division contains tools involving phylogenetic trees. Alignments are annotated with analytical results and modification history using
our PRAED format. A miscellaneous Tools section and Help framework are also available. EGenBio was developed around our comparative genomic research and a prototype database of mtDNA genomes. It utilizes MySQL-relational databases and dynamic page generation, and calls numerous custom programs.
Description
From The Third Annual Conference of the MidSouth Computational Biology and Bioinformatics Society Baton Rouge, Louisiana. 2–4 March, 2006. © 2006 Nahum et al; licensee BioMed Central Ltd.
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