Scores of distinguished biologists from around the world come to the MBL to collaborate and conduct research. They use marine and other organisms as model systems for their research.

These researchers participate in a number of established MBL groups including but not limited to:

  • MBL Summer Research Fellows
  • Dart Scholars
  • Grass Faculty Awardees
  • NeuroImaging Cluster
  • Grass Fellows

Recent Submissions

  • The solute carrier SLC9C1 is a Na+/H+-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding 

    Windler, Florian; Bönigk, Wolfgang; Körschen, Heinz Gerd; Grahn, Elena; Strünker, Timo; Seifert, Reinhard; Kaupp, U. Benjamin (Nature Publishing Group, 2018-07-18)
    Voltage-sensing (VSD) and cyclic nucleotide-binding domains (CNBD) gate ion channels for rapid electrical signaling. By contrast, solute carriers (SLCs) that passively redistribute substrates are gated by their substrates ...
  • Systems Biology of the human microbiome 

    Peñalver Bernabé, Beatriz; Cralle, Lauren; Gilbert, Jack A. (2017-09)
    Recent research has shown that the microbiome—a collection of microorganisms, including bacteria, fungi, and viruses, living on and in a host—are of extraordinary importance in human health, even from conception and ...
  • Metagenomic analysis of basal ice from an Alaskan glacier 

    Kayani, Masood ur Rehman; Doyle, Shawn M.; Sangwan, Naseer; Wang, Guanqun; Gilbert, Jack A.; Christner, Brent C.; Zhu, Ting F. (BMC, 2018-07-05)
    Glaciers cover ~ 10% of land but are among the least explored environments on Earth. The basal portion of glaciers often harbors unique aquatic microbial ecosystems in the absence of sunlight, and knowledge on the microbial ...
  • Electrical synapses enhance and accelerate interneuron recruitment in response to coincident and sequential excitation 

    Alcami, Pepe (Frontiers Media, 2018-06-19)
    Electrical synapses are ubiquitous in interneuron networks. They form intercellular pathways, allowing electrical currents to leak between coupled interneurons. I explored the impact of electrical coupling on the integration ...
  • A sialylated voltage-dependent Ca2+ channel binds hemagglutinin and mediates influenza a virus entry into mammalian cells 

    Fujioka, Yoichiro; Nishide, Shinya; Ose, Toyoyuki; Suzuki, Tadaki; Kato, Izumi; Fukuhara, Hideo; Fujioka, Mari; Horiuchi, Kosui; Satoh, Aya O.; Nepal, Prabha; Kashiwagi, Sayaka; Wang, Jing; Horiguchi, Mika; Sato, Yuko; Paudel, Sarad; Nanbo, Asuka; Miyazaki, Tadaaki; Hasegawa, Hideki; Maenaka, Katsumi; Ohba, Yusuke (2018-04)
    Influenza A virus (IAV) infection is initiated by the attachment of the viral glycoprotein hemagglutinin (HA) to sialic acid on the host cell surface. However, the sialic acid– containing receptor crucial for IAV infection ...
  • Network-guided genomic and metagenomic analysis of the faecal microbiota of the critically endangered kakapo 

    Waite, David W.; Dsouza, Melissa; Sekiguchi, Yuji; Hugenholtz, Philip; Taylor, Michael W. (Nature Publishing Group, 2018-05-25)
    The kakapo is a critically endangered, herbivorous parrot endemic to New Zealand. The kakapo hindgut hosts a dense microbial community of low taxonomic diversity, typically dominated by Escherichia fergusonii, and has ...
  • Soil bacterial diversity is associated with human population density in urban greenspaces 

    Wang, Haitao; Cheng, Minying; Dsouza, Melissa; Weisenhorn, Pamela B.; Zheng, Tianling; Gilbert, Jack A. (2018-04)
    Urban greenspaces provide extensive ecosystem services, including pollutant remediation, water management, carbon maintenance, and nutrient cycling. However, while the urban soil microbiota underpin these services, we still ...
  • Current understanding of the human microbiome 

    Gilbert, Jack A.; Blaser, Martin J.; Caporaso, J. Gregory; Jansson, Janet K.; Lynch, Susan V.; Knight, Rob (2018-02-05)
    Our understanding of the link between the human microbiome and disease, including obesity, inflammatory bowel disease, arthritis and autism, is rapidly expanding. Improvements in the throughput and accuracy of DNA sequencing ...
  • Prc1E and Kif4A control microtubule organization within and between large Xenopus egg asters 

    Nguyen, Phuong A.; Field, Christine M.; Mitchison, Timothy J. (American Society for Cell Biology, 2018-03-23)
    The cleavage furrow in Xenopus zygotes is positioned by two large microtubule asters that grow out from the poles of the first mitotic spindle. Where these asters meet at the midplane, they assemble a disk-shaped interaction ...
  • ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation 

    Sama, Reddy Ranjith K.; Fallini, Claudia; Gatto, Rodolfo; McKeon, Jeanne E.; Song, Yuyu; Rotunno, Melissa S.; Penaranda, Saul; Abdurakhmanov, Izrail; Landers, John E.; Morfini, Gerardo A.; Brady, Scott T.; Bosco, Daryl A. (Nature Publishing Group, 2017-03-08)
    Mutations in Fused in Sarcoma/Translocated in Liposarcoma (FUS) cause familial forms of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by progressive axonal degeneration mainly affecting ...
  • Resilience in moving water : effects of turbulence on the predatory impact of the lobate ctenophore Mnemiopsis leidyi 

    Jaspers, Cornelia; Costello, John H.; Sutherland, Kelly R.; Gemmell, Brad J.; Lucas, Kelsey N.; Tackett, Jennifer; Dodge, Kara L.; Colin, Sean P. (John Wiley & Sons, 2017-08-14)
    Despite its delicate morphology, the lobate ctenophore Mnemiopsis leidyi thrives in coastal ecosystems as an influential zooplankton predator. Coastal ecosystems are often characterized as energetic systems with high levels ...
  • Prion protein inhibits fast axonal transport through a mechanism involving casein kinase 2 

    Zamponi, Emiliano; Buratti, Fiamma; Cataldi, Gabriel; Caicedo, Hector Hugo; Song, Yuyu; Jungbauer, Lisa M.; LaDu, Mary J.; Bisbal, Mariano; Lorenzo, Lorenzo; Ma, Jiyan; Helguera, Pablo R.; Morfini, Gerardo A.; Brady, Scott T.; Pigino, Gustavo F. (Public Library of Science, 2017-12-20)
    Prion diseases include a number of progressive neuropathies involving conformational changes in cellular prion protein (PrPc) that may be fatal sporadic, familial or infectious. Pathological evidence indicated that neurons ...
  • Widespread utilization of passive energy recapture in swimming medusae 

    Gemmell, Brad J.; Colin, Sean P.; Costello, John H. (The Company of Biologists, 2017-11-27)
    Recently, it has been shown that some medusae are capable of swimming very efficiently, i.e. with a low cost of transport, and that this is in part due to passive energy recapture (PER) which occurs during bell relaxation. ...
  • Single-fluorophore orientation determination with multiview polarized illumination : modeling and microscope design 

    Chandler, Talon; Mehta, Shalin B.; Shroff, Hari; Oldenbourg, Rudolf; La Riviere, Patrick J. (Optical Society, 2017-12-01)
    We investigate the use of polarized illumination in multiview microscopes for determining the orientation of single-molecule fluorescence transition dipoles. First, we relate the orientation of single dipoles to measurable ...
  • Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration 

    Nordenfelt, Pontus; Moore, Travis I.; Mehta, Shalin B.; Kalappurakkal, Joseph Mathew; Swaminathan, Vinay; Koga, Nobuyasu; Lambert, Talley J.; Baker, David; Waters, Jennifer C.; Oldenbourg, Rudolf; Tani, Tomomi; Mayor, Satyajit; Waterman, Clare M.; Springer, Timothy (Nature Publishing Group, 2017-12-11)
    Integrin αβ heterodimer cell surface receptors mediate adhesive interactions that provide traction for cell migration. Here, we test whether the integrin, when engaged to an extracellular ligand and the cytoskeleton, adopts ...
  • Reflective imaging improves spatiotemporal resolution and collection efficiency in light sheet microscopy 

    Wu, Yicong; Kumar, Abhishek; Smith, Corey; Ardiel, Evan L.; Chandris, Panagiotis; Christensen, Ryan; Rey-Suarez, Ivan; Guo, Min; Vishwasrao, Harshad D.; Chen, Jiji; Tang, Jianyong; Upadhyaya, Arpita; La Riviere, Patrick J.; Shroff, Hari (Nature Publishing Group, 2017-11-13)
    Light-sheet fluorescence microscopy (LSFM) enables high-speed, high-resolution, and gentle imaging of live specimens over extended periods. Here we describe a technique that improves the spatiotemporal resolution and ...
  • Sodium dynamics in pyramidal neuron dendritic spines : synaptically evoked entry predominantly through AMPA receptors and removal by diffusion 

    Miyazaki, Kenichi; Ross, William N. (Society for Neuroscience, 2017-10-11)
    Dendritic spines are key elements underlying synaptic integration and cellular plasticity, but many features of these important structures are not known or are controversial. We examined these properties using newly developed ...
  • Quantitative perspectives on fifty years of the Journal of the History of Biology 

    Peirson, Erick; Bottino, Erin; Damerow, Julia L.; Laubichler, Manfred D. (2017-10)
    Journal of the History of Biology provides a fifty-year long record for examining the evolution of the history of biology as a scholarly discipline. In this paper, we present a new dataset and preliminary quantitative ...
  • Improved bacterial 16S rRNA gene (V4 and V4-5) and fungal internal transcribed spacer marker gene primers for microbial community surveys 

    Walters, William; Hyde, Embriette R.; Berg-Lyons, Donna; Ackermann, Gail; Humphrey, Greg; Parada, Alma; Gilbert, Jack A.; Jansson, Janet K.; Caporaso, J. Gregory; Fuhrman, Jed A.; Apprill, Amy; Knight, Rob (American Society for Microbiology, 2015-12-22)
    Designing primers for PCR-based taxonomic surveys that amplify a broad range of phylotypes in varied community samples is a difficult challenge, and the comparability of data sets amplified with varied primers requires ...
  • Distinct biogeographic patterns for archaea, bacteria, and fungi along the vegetation gradient at the continental scale in Eastern China 

    Ma, Bin; Dai, Zhongmin; Wang, Haizhen; Dsouza, Melissa; Liu, Xingmei; He, Yan; Wu, Jianjun; Rodrigues, Jorge L. M.; Gilbert, Jack A.; Brookes, Philip C.; Xu, Jianming (American Society for Microbiology, 2017-02-07)
    The natural forest ecosystem in Eastern China, from tropical forest to boreal forest, has declined due to cropland development during the last 300 years, yet little is known about the historical biogeographic patterns and ...

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