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dc.contributor.authorFaber, Donald S.  Concept link
dc.contributor.authorPereda, Alberto E.  Concept link
dc.identifier.citationFrontiers in Molecular Neuroscience 11 (2018): 427en_US
dc.description© The Author(s), 2018. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Frontiers in Molecular Neuroscience 11 (2018): 427, doi:10.3389/fnmol.2018.00427.en_US
dc.description.abstractElectrical signaling is a cardinal feature of the nervous system and endows it with the capability of quickly reacting to changes in the environment. Although synaptic communication between nerve cells is perceived to be mainly chemically mediated, electrical synaptic interactions also occur. Two different strategies are responsible for electrical communication between neurons. One is the consequence of low resistance intercellular pathways, called “gap junctions”, for the spread of electrical currents between the interior of two cells. The second occurs in the absence of cell-to-cell contacts and is a consequence of the extracellular electrical fields generated by the electrical activity of neurons. Here, we place present notions about electrical transmission in a historical perspective and contrast the contributions of the two different forms of electrical communication to brain function.en_US
dc.description.sponsorshipThis research was supported by National Institutes of Health grants DC03186, DC011099, NS055726, NS085772 and NS0552827 to AP.en_US
dc.publisherFrontiers Mediaen_US
dc.rightsAttribution 4.0 International*
dc.subjectSynaptic communicationen_US
dc.subjectElectrical synapseen_US
dc.subjectGap junctionen_US
dc.subjectElectric fielden_US
dc.titleTwo forms of electrical transmission between neuronsen_US

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Attribution 4.0 International
Except where otherwise noted, this item's license is described as Attribution 4.0 International