Concerns about quadrupole ICP-MS lead isotopic data and interpretations in the environment and health fields
Kamenov, George D.
MetadataShow full item record
There has been a massive increase in recent years of the use of lead (Pb) isotopes in attempts to better understand sources and pathways of Pb in the environment and in man or experimental animals. Unfortunately, there have been many cases where the quality of the isotopic data, especially that obtained by quadrupole inductively coupled plasma mass spectrometry (Q-ICP-MS), are questionable, resulting in questionable identification of potential sources, which, in turn, impacts study interpretation and conclusions. We present several cases where the isotopic data have compromised interpretation because of the use of only the major isotopes 208Pb/206Pb and 207Pb/206Pb, or their graphing in other combinations. We also present some examples comparing high precision data from thermal ionization (TIMS) or multi-collector plasma mass spectrometry (MC-ICP-MS) to illustrate the deficiency in the Q-ICP-MS data. In addition, we present cases where Pb isotopic ratios measured on Q-ICP-MS are virtually impossible for terrestrial samples. We also evaluate the Pb isotopic data for rat studies, which had concluded that Pb isotopic fractionation occurs between different organs and suggest that this notion of biological fractionation of Pb as an explanation for isotopic differences is not valid. Overall, the brief review of these case studies shows that Q-ICP-MS as commonly practiced is not a suitable technique for precise and accurate Pb isotopic analysis in the environment and health fields
© The Author(s), 2018. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in International Journal of Environmental Research and Public Health 15 (2018): 723, doi:10.3390/ijerph15040723.
Suggested CitationArticle: Gulson, Brian, Kamenov, George D., Manton, William, Rabinowitz, Michael, "Concerns about quadrupole ICP-MS lead isotopic data and interpretations in the environment and health fields", International Journal of Environmental Research and Public Health 15 (2018): 723, DOI:10.3390/ijerph15040723, https://hdl.handle.net/1912/10258
The following license files are associated with this item:
Showing items related by title, author, creator and subject.
Lima, Ana Lucia Cessel de (Massachusetts Institute of Technology and Woods Hole Oceanographic Institution, 2004-06)The most ubiquitous source of polycyclic aromatic hydrocarbons (PAHs) to the environment is incomplete combustion. This study generated a high-resolution historical record of pyrogenic PAH emissions since pre-industrial ...
Controls on stable isotope and trace metal uptake in Neogloboquadrina pachyderma (sinistral) from an Antarctic sea-ice environment Hendry, Katharine R.; Rickaby, Rosalind E. M.; Meredith, Michael P.; Elderfield, Henry (2008-11)The polar foraminifera Neogloboquadrina pachyderma (sinistral) dominates assemblages from the high latitude Southern Ocean, which is a key region for paleoclimate studies. Here, we use N. pachyderma (s.) harvested from ...
Ecosystem metabolism in salt marsh tidal creeks and ponds : applying triple oxygen isotopes and other gas tracers to novel environments Howard, Evan M. (Massachusetts Institute of Technology and Woods Hole Oceanographic Institution, 2017-02)Salt marshes are physically, chemically, and biologically dynamic environments found globally at temperate latitudes. Tidal creeks and marshtop ponds may expand at the expense of productive grass-covered marsh platform. ...