James-Zorn Christina

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James-Zorn
First Name
Christina
ORCID
0000-0001-5495-4588

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  • Article
    Normal table of Xenopus development: a new graphical resource
    (The Company of Biologists, 2022-07-14) Zahn, Natalya ; James-Zorn, Christina ; Ponferrada, Virgilio G. ; Adams, Dany S. ; Grzymkowski, Julia ; Buchholz, Daniel R. ; Nascone-Yoder, Nanette M. ; Horb, Marko E. ; Moody, Sally A. ; Vize, Peter D. ; Zorn, Aaron M.
    Normal tables of development are essential for studies of embryogenesis, serving as an important resource for model organisms, including the frog Xenopus laevis. Xenopus has long been used to study developmental and cell biology, and is an increasingly important model for human birth defects and disease, genomics, proteomics and toxicology. Scientists utilize Nieuwkoop and Faber's classic ‘Normal Table of Xenopus laevis (Daudin)’ and accompanying illustrations to enable experimental reproducibility and reuse the illustrations in new publications and teaching. However, it is no longer possible to obtain permission for these copyrighted illustrations. We present 133 new, high-quality illustrations of X. laevis development from fertilization to metamorphosis, with additional views that were not available in the original collection. All the images are available on Xenbase, the Xenopus knowledgebase (http://www.xenbase.org/entry/zahn.do), for download and reuse under an attributable, non-commercial creative commons license. Additionally, we have compiled a ‘Landmarks Table’ of key morphological features and marker gene expression that can be used to distinguish stages quickly and reliably (https://www.xenbase.org/entry/landmarks-table.do). This new open-access resource will facilitate Xenopus research and teaching in the decades to come.
  • Article
    Xenopus resources: Transgenic, inbred and mutant animals, training opportunities, and web-based support.
    (Frontiers Media, 2019-04-25) Horb, Marko E. ; Wlizla, Marcin ; Abu-Daya, Anita ; McNamara, Sean ; Gajdasik, Dominika ; Igawa, Takeshi ; Suzuki, Atsushi ; Ogino, Hajime ; Noble, Anna ; Robert, Jacques ; James-Zorn, Christina ; Guille, Matthew ; Nicolas, Morgane ; Lafond, Thomas ; Boujard, Daniel ; Audic, Yann ; Guillet, Brigitte ; Centre de Ressource Biologique Xenope team in France
    Two species of the clawed frog family, Xenopus laevis and X. tropicalis, are widely used as tools to investigate both normal and disease-state biochemistry, genetics, cell biology, and developmental biology. To support both frog specialist and non-specialist scientists needing access to these models for their research, a number of centralized resources exist around the world. These include centers that hold live and frozen stocks of transgenic, inbred and mutant animals and centers that hold molecular resources. This infrastructure is supported by a model organism database. Here, we describe much of this infrastructure and encourage the community to make the best use of it and to guide the resource centers in developing new lines and libraries.