Now showing items 1-3 of 3

    • Micron-scale plasma membrane curvature is recognized by the septin cytoskeleton 

      Bridges, Andrew A.; Jentzsch, Maximilian S.; Oakes, Patrick W.; Occhipinti, Patricia; Gladfelter, Amy S. (Rockefeller University Press, 2016-04-04)
      Cells change shape in response to diverse environmental and developmental conditions, creating topologies with micron-scale features. Although individual proteins can sense nanometer-scale membrane curvature, it is unclear ...
    • Septin assemblies form by diffusion-driven annealing on membranes 

      Bridges, Andrew A.; Zhang, Huaiying; Mehta, Shalin B.; Occhipinti, Patricia; Tani, Tomomi; Gladfelter, Amy S. (2013-12)
      Septins assemble into filaments and higher-order structures that act as scaffolds for diverse cell functions including cytokinesis, cell polarity, and membrane remodeling. Despite their conserved role in cell organization, ...
    • Septin filaments exhibit a dynamic, paired organization that is conserved from yeast to mammals 

      DeMay, Bradley S.; Bai, Xiaobo; Howard, Louisa; Occhipinti, Patricia; Meseroll, Rebecca A.; Spiliotis, Elias T.; Oldenbourg, Rudolf; Gladfelter, Amy S. (Rockefeller University Press, 2011-06-13)
      The septins are conserved, GTP-binding proteins important for cytokinesis, membrane compartmentalization, and exocytosis. However, it is unknown how septins are arranged within higher-order structures in cells. To determine ...