Length control of the metaphase spindle

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Title:	Length control of the metaphase spindle
Author:	Goshima, Gohta; Wollman, Roy; Stuurman, Nico; Scholey, Jonathan M.; Vale, Ronald D.
Abstract:	The pole-to-pole distance of the metaphase spindle is reasonably constant in a given cell type; in the case of vertebrate female oocytes, this steady state length can be maintained for substantial lengths of time, during which time microtubules remain highly dynamic. While a number of molecular perturbations have been shown to influence spindle length, a global understanding of the factors that determine metaphase spindle length has not been achieved.
Description:	Author Posting. © The Authors, 2005. This is the author's version of the work. It is posted here by permission of Elsevier B. V. for personal use, not for redistribution. The definitive version was published in Current Biology 15 (2005): 1979-1988, doi:10.1016/j.cub.2005.09.054.
As published:	http://dx.doi.org/10.1016/j.cub.2005.09.054
Citable URI:	http://hdl.handle.net/1912/291
Date:	2005-09-30

Files	Size	Format	View	Description
Goshima_etal_Oct12FINAL.doc	569.3Kb	Microsoft Word	View/Open	Author's final draft
figures.pdf	300.4Kb	PDF	View/Open	Figures
1. Klp67A+Colchicine.mov	2.484Mb	QuickTime video	View/Open	Klp67A-GFP Dynamics upon Colchicine Treatment
2. Control.FSM.mov	2.157Mb	QuickTime video	View/Open	Fluorescent Speckle Microscopy of GFP-Tubulin in Spindles without RNAi Treatment
3. Klp61F_RNAi.FSM.mov	6.657Mb	QuickTime video	View/Open	Fluorescent Speckle Microscopy of GFP-Tubulin in Spindles after Klp61F RNAi