The liver transcriptome of suckermouth armoured catfish (Pterygoplichthys anisitsi, Loricariidae) : identification of expansions in defensome gene families
The liver transcriptome of suckermouth armoured catfish (Pterygoplichthys anisitsi, Loricariidae) : identification of expansions in defensome gene families
Date
2016-12
Authors
Parente, Thiago
Moreira, Daniel A.
Magalhaes, Maithê G. P.
de Andrade, Paula C. C.
Furtado, Carolina
Haas, Brian J.
Stegeman, John J.
Hahn, Mark E.
Moreira, Daniel A.
Magalhaes, Maithê G. P.
de Andrade, Paula C. C.
Furtado, Carolina
Haas, Brian J.
Stegeman, John J.
Hahn, Mark E.
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Keywords
RNA-Seq
P450
SULT
ABC transporters
Nuclear Receptors
P450
SULT
ABC transporters
Nuclear Receptors
Abstract
Pterygoplichthys is a genus of related suckermouth armoured catfish native to
South America that has invaded tropical and subtropical regions worldwide.
Physiological features, including an augmented resistance to organic xenobiotics,
may have aided their settlement in foreign habitats. The liver transcriptome of
Pterygoplichthys anisitsi was sequenced and used to characterize the diversity of
mRNAs potentially involved in the responses to natural and anthropogenic
chemicals. In total, 66,642 transcripts were assembled. Among the identified
defensome genes, cytochromes P450 (CYP) were the most abundant, followed by
nuclear receptors (NR), sulfotransferases (SULT) and ATP binding cassette
transporters (ABC). A novel expansion in the CYP2Y subfamily was identified, as
well as an independent expansion of the CYP2AAs. Two expansions were also
observed among SULT1. Thirty-nine transcripts were classified into twelve
subfamilies of NR, while 21 encoded ABC transporters. The diversity of defensome
transcripts sequenced herein could contribute to this species resistance to organic
xenobiotics.
Description
© The Author(s), 2016. This is the author's version of the work. It is posted here under a nonexclusive, irrevocable, paid-up, worldwide license granted to WHOI. It is made available for personal use, not for redistribution. The definitive version was published in Marine Pollution Bulletin 115 (2017): 352-361, doi:10.1016/j.marpolbul.2016.12.012.