Dive, food and exercise effects on blood microparticles in Steller sea lions (Eumetopias jubatus) : exploring a biomarker for decompression sickness
Moore, Michael J.
Trites, Andrew W.
Rosen, David A. S.
Thom, Stephen R.
MetadataShow full item record
Recent studies of stranded marine mammals indicate that exposure to underwater military sonar may induce pathophysiological responses consistent with decompression sickness (DCS). However, DCS has been difficult to diagnose in marine mammals. We investigated whether blood microparticles (MPs, measured as number/μl plasma), which increase in response to decompression stress in terrestrial mammals, are a suitable biomarker for DCS in marine mammals. We obtained blood samples from trained Steller sea lions (Eumetopias jubatus, 4 adult females) wearing time-depth recorders that dove to predetermined depths (either 5 or 50 m). We hypothesized that MPs would be positively related to decompression stress (depth and duration underwater). We also tested the effect of feeding and exercise in isolation on MPs using the same blood sampling protocol. We found that feeding and exercise had no effect on blood MP levels, but that diving caused MPs to increase. However, blood MP levels did not correlate with diving depth, relative time underwater, and presumably decompression stress―possibly indicating acclimation following repeated exposure to depth.
Author Posting. © The Author(s), 2016. This is the author's version of the work. It is posted here by permission of American Physiological Society for personal use, not for redistribution. The definitive version was published in American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 310 (2016): R596-R601, doi:10.1152/ajpregu.00512.2015.
The publisher requires that this item be embargoed until 2017-02-03. Please check back after 2017-02-03.
Showing items related by title, author, creator and subject.
Estimated tissue and blood N2 levels and risk of decompression sickness in deep-, intermediate-, and shallow-diving toothed whales during exposure to naval sonar Kvadsheim, P. H.; Miller, Patrick J. O.; Tyack, Peter L.; Sivle, L. D.; Lam, F. P. A.; Fahlman, Andreas (Frontiers Media, 2012-05-10)Naval sonar has been accused of causing whale stranding by a mechanism which increases formation of tissue N2 gas bubbles. Increased tissue and blood N2 levels, and thereby increased risk of decompression sickness (DCS), ...
Hooker, Sascha K.; Fahlman, Andreas; Moore, Michael J.; Aguilar De Soto, Natacha; Bernaldo de Quiros, Yara; Brubakk, A. O.; Costa, Daniel P.; Costidis, Alexander M.; Dennison, Sophie; Falke, K. J.; Fernandez, Antonio; Ferrigno, Massimo; Fitz-Clarke, J. R.; Garner, M. M.; Houser, Dorian S.; Jepson, Paul D.; Ketten, Darlene R.; Kvadsheim, P. H.; Madsen, Peter T.; Pollock, N. W.; Rotstein, David S.; Rowles, Teresa K.; Simmons, S. E.; Van Bonn, William; Weathersby, P. K.; Weise, M. J.; Williams, T. M.; Tyack, Peter L. (Royal Society, 2011-12-21)Decompression sickness (DCS; ‘the bends’) is a disease associated with gas uptake at pressure. The basic pathology and cause are relatively well known to human divers. Breath-hold diving marine mammals were thought to be ...
Compositional discrimination of decompression and decomposition gas bubbles in bycaught seals and dolphins Bernaldo de Quiros, Yara; Seewald, Jeffrey S.; Sylva, Sean P.; Greer, Bill; Niemeyer, Misty E.; Bogomolni, Andrea L.; Moore, Michael J. (Public Library of Science, 2013-12-19)Gas bubbles in marine mammals entangled and drowned in gillnets have been previously described by computed tomography, gross examination and histopathology. The absence of bacteria or autolytic changes in the tissues of ...