Static inflation and deflation pressure–volume curves from excised lungs of marine mammals
Static inflation and deflation pressure–volume curves from excised lungs of marine mammals
Date
2011-06-28
Authors
Fahlman, Andreas
Loring, Stephen H.
Ferrigno, Massimo
Moore, Colby D.
Early, Greg A.
Niemeyer, Misty E.
Lentell, Betty J.
Wenzel, Frederick W.
Joy, Ruth
Moore, Michael J.
Loring, Stephen H.
Ferrigno, Massimo
Moore, Colby D.
Early, Greg A.
Niemeyer, Misty E.
Lentell, Betty J.
Wenzel, Frederick W.
Joy, Ruth
Moore, Michael J.
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Keywords
Lung mechanics
Total lung capacity
Minimum air volume
Excised lung
Diving physiology
Total lung capacity
Minimum air volume
Excised lung
Diving physiology
Abstract
Excised lungs from 8 marine mammal species (harp [Pagophilus groenlandicus],
harbor [Phoca vitulina], and gray seal [Halichoerus grypus], Atlantic white-sided
[Lagenorhynchus acutus], common [Delphinus delphis] and Risso's dolphin [Grampus griseus],
long finned pilot whale [Globicephala melas], and harbor porpoise [Phocoena phocoena]) were
used to determine minimum air volume of the relaxed lung (MAV, n = 15) and the elastic
properties (pressure-volume curves, n = 24) of the respiratory system, and total lung capacity
(TLC). Our data indicate that mass-specific TLC (sTLC, l • kg-1) does not differ between species
or groups (odontocete vs. phocid) and agree with that estimated (TLCest) from body mass (Mb)
by: TLCest = 0.135 • Mb
0.92. Measured MAV was on average 7% of TLC, with a range from 0%
to 16%. The pressure-volume curves were similar among species on inflation but diverged
during deflation in phocids as compared with odontocetes. These differences provide a structural
basis for observed species differences in depth at which lungs collapse and gas exchange ceases.
Description
Author Posting. © The Author(s), 2011. This is the author's version of the work. It is posted here by permission of The Company of Biologists for personal use, not for redistribution. The definitive version was published in Journal of Experimental Biology 214 (2011): 3822-3828, doi:10.1242/jeb.056366.